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A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype.
Kota S, Hou S, Guerrant W, Madoux F, Troutman S, Fernandez-Vega V, Alekseeva N, Madala N, Scampavia L, Kissil J, Spicer TP. Kota S, et al. Among authors: Madoux F. Oncogene. 2018 Aug;37(32):4372-4384. doi: 10.1038/s41388-018-0257-5. Epub 2018 May 10. Oncogene. 2018. PMID: 29743592 Free PMC article.
Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening.
Hou S, Tiriac H, Sridharan BP, Scampavia L, Madoux F, Seldin J, Souza GR, Watson D, Tuveson D, Spicer TP. Hou S, et al. Among authors: Madoux F. Version 2. SLAS Discov. 2018 Jul;23(6):574-584. doi: 10.1177/2472555218766842. Epub 2018 Apr 19. SLAS Discov. 2018. PMID: 29673279 Free PMC article.
Improved Scalability of Neuron-Based Phenotypic Screening Assays for Therapeutic Discovery in Neuropsychiatric Disorders.
Spicer TP, Hubbs C, Vaissiere T, Collia D, Rojas C, Kilinc M, Vick K, Madoux F, Baillargeon P, Shumate J, Martemyanov KA, Page DT, Puthanveettil S, Hodder P, Davis R, Miller CA, Scampavia L, Rumbaugh G. Spicer TP, et al. Among authors: Madoux F. Mol Neuropsychiatry. 2018 Feb;3(3):141-150. doi: 10.1159/000481731. Epub 2017 Nov 17. Mol Neuropsychiatry. 2018. PMID: 29594133 Free PMC article.
Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4).
Smith E, Chase P, Niswender CM, Utley TJ, Sheffler DJ, Noetzel MJ, Lamsal A, Wood MR, Conn PJ, Lindsley CW, Madoux F, Acosta M, Scampavia L, Spicer T, Hodder P. Smith E, et al. Among authors: Madoux F. J Biomol Screen. 2015 Aug;20(7):858-68. doi: 10.1177/1087057115581770. Epub 2015 Apr 15. J Biomol Screen. 2015. PMID: 25877150 Free PMC article.
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