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Page 1
Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy.
Crean RM, MacLachlan BJ, Madura F, Whalley T, Rizkallah PJ, Holland CJ, McMurran C, Harper S, Godkin A, Sewell AK, Pudney CR, van der Kamp MW, Cole DK. Crean RM, et al. Among authors: madura f. Mol Ther Oncolytics. 2020 Jul 31;18:443-456. doi: 10.1016/j.omto.2020.07.008. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32913893 Free PMC article.
TCR/pMHC Optimized Protein crystallization Screen.
Bulek AM, Madura F, Fuller A, Holland CJ, Schauenburg AJ, Sewell AK, Rizkallah PJ, Cole DK. Bulek AM, et al. Among authors: madura f. J Immunol Methods. 2012 Aug 31;382(1-2):203-10. doi: 10.1016/j.jim.2012.06.007. Epub 2012 Jun 15. J Immunol Methods. 2012. PMID: 22705983 Free PMC article.
T-cell receptor specificity maintained by altered thermodynamics.
Madura F, Rizkallah PJ, Miles KM, Holland CJ, Bulek AM, Fuller A, Schauenburg AJ, Miles JJ, Liddy N, Sami M, Li Y, Hossain M, Baker BM, Jakobsen BK, Sewell AK, Cole DK. Madura F, et al. J Biol Chem. 2013 Jun 28;288(26):18766-75. doi: 10.1074/jbc.M113.464560. Epub 2013 May 22. J Biol Chem. 2013. PMID: 23698002 Free PMC article.
T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
Cole DK, Miles KM, Madura F, Holland CJ, Schauenburg AJ, Godkin AJ, Bulek AM, Fuller A, Akpovwa HJ, Pymm PG, Liddy N, Sami M, Li Y, Rizkallah PJ, Jakobsen BK, Sewell AK. Cole DK, et al. Among authors: madura f. J Biol Chem. 2014 Jan 10;289(2):628-38. doi: 10.1074/jbc.M113.522110. Epub 2013 Nov 6. J Biol Chem. 2014. PMID: 24196962 Free PMC article.
TCR-induced alteration of primary MHC peptide anchor residue.
Madura F, Rizkallah PJ, Legut M, Holland CJ, Fuller A, Bulek A, Schauenburg AJ, Trimby A, Hopkins JR, Wells SA, Godkin A, Miles JJ, Sami M, Li Y, Liddy N, Jakobsen BK, Loveridge EJ, Cole DK, Sewell AK. Madura F, et al. Eur J Immunol. 2019 Jul;49(7):1052-1066. doi: 10.1002/eji.201948085. Epub 2019 May 27. Eur J Immunol. 2019. PMID: 31091334 Free PMC article.
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Bulek AM, Cole DK, Skowera A, Dolton G, Gras S, Madura F, Fuller A, Miles JJ, Gostick E, Price DA, Drijfhout JW, Knight RR, Huang GC, Lissin N, Molloy PE, Wooldridge L, Jakobsen BK, Rossjohn J, Peakman M, Rizkallah PJ, Sewell AK. Bulek AM, et al. Among authors: madura f. Nat Immunol. 2012 Jan 15;13(3):283-9. doi: 10.1038/ni.2206. Nat Immunol. 2012. PMID: 22245737 Free PMC article.
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting.
Ekeruche-Makinde J, Clement M, Cole DK, Edwards ES, Ladell K, Miles JJ, Matthews KK, Fuller A, Lloyd KA, Madura F, Dolton GM, Pentier J, Lissina A, Gostick E, Baxter TK, Baker BM, Rizkallah PJ, Price DA, Wooldridge L, Sewell AK. Ekeruche-Makinde J, et al. Among authors: madura f. J Biol Chem. 2012 Oct 26;287(44):37269-81. doi: 10.1074/jbc.M112.386409. Epub 2012 Sep 5. J Biol Chem. 2012. PMID: 22952231 Free PMC article.
12 results