Maechler P - Search Results

1

Role of mitochondria in metabolism-secretion coupling of insulin release in the pancreatic beta-cell.

Maechler P, Wollheim CB. Maechler P, et al. Biofactors. 1998;8(3-4):255-62. doi: 10.1002/biof.5520080313. Biofactors. 1998. PMID: 9914827 Review.

2

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

Maechler P, Kennedy ED, Pozzan T, Wollheim CB. Maechler P, et al. EMBO J. 1997 Jul 1;16(13):3833-41. doi: 10.1093/emboj/16.13.3833. EMBO J. 1997. PMID: 9233793 Free PMC article.

3

Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase.

Maechler P, Wang H, Wollheim CB. Maechler P, et al. FEBS Lett. 1998 Feb 6;422(3):328-32. doi: 10.1016/s0014-5793(97)01618-9. FEBS Lett. 1998. PMID: 9498809

4

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

Kennedy ED, Maechler P, Wollheim CB. Kennedy ED, et al. Among authors: maechler p. Diabetes. 1998 Mar;47(3):374-80. doi: 10.2337/diabetes.47.3.374. Diabetes. 1998. PMID: 9519742

5

Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell.

Maechler P, Kennedy ED, Wang H, Wollheim CB. Maechler P, et al. J Biol Chem. 1998 Aug 14;273(33):20770-8. doi: 10.1074/jbc.273.33.20770. J Biol Chem. 1998. PMID: 9694821

6

Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.

Wang H, Maechler P, Hagenfeldt KA, Wollheim CB. Wang H, et al. Among authors: maechler p. EMBO J. 1998 Nov 16;17(22):6701-13. doi: 10.1093/emboj/17.22.6701. EMBO J. 1998. PMID: 9822613 Free PMC article.

7

Free radical modulation of insulin release in INS-1 cells exposed to alloxan.

Janjic D, Maechler P, Sekine N, Bartley C, Annen AS, Wolheim CB. Janjic D, et al. Among authors: maechler p. Biochem Pharmacol. 1999 Mar 15;57(6):639-48. doi: 10.1016/s0006-2952(98)00346-3. Biochem Pharmacol. 1999. PMID: 10037448

8

Reactive oxygen metabolites increase mitochondrial calcium in endothelial cells: implication of the Ca2+/Na+ exchanger.

Jornot L, Maechler P, Wollheim CB, Junod AF. Jornot L, et al. Among authors: maechler p. J Cell Sci. 1999 Apr;112 ( Pt 7):1013-22. J Cell Sci. 1999. PMID: 10198283

9

Secretagogues modulate the calcium concentration in the endoplasmic reticulum of insulin-secreting cells. Studies in aequorin-expressing intact and permeabilized ins-1 cells.

Maechler P, Kennedy ED, Sebö E, Valeva A, Pozzan T, Wollheim CB. Maechler P, et al. J Biol Chem. 1999 Apr 30;274(18):12583-92. doi: 10.1074/jbc.274.18.12583. J Biol Chem. 1999. PMID: 10212237

10

Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.

Maechler P, Jornot L, Wollheim CB. Maechler P, et al. J Biol Chem. 1999 Sep 24;274(39):27905-13. doi: 10.1074/jbc.274.39.27905. J Biol Chem. 1999. PMID: 10488138

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