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The Prediction of the Relative Importance of CYP3A/P-glycoprotein to the Nonlinear Intestinal Absorption of Drugs by Advanced Compartmental Absorption and Transit Model.
Takano J, Maeda K, Bolger MB, Sugiyama Y. Takano J, et al. Among authors: maeda k. Drug Metab Dispos. 2016 Nov;44(11):1808-1818. doi: 10.1124/dmd.116.070011. Epub 2016 Aug 18. Drug Metab Dispos. 2016. PMID: 27538919
Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin.
Hirano M, Maeda K, Hayashi H, Kusuhara H, Sugiyama Y. Hirano M, et al. Among authors: maeda k. J Pharmacol Exp Ther. 2005 Aug;314(2):876-82. doi: 10.1124/jpet.105.084830. Epub 2005 May 18. J Pharmacol Exp Ther. 2005. PMID: 15901796
Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.
Matsushima S, Maeda K, Kondo C, Hirano M, Sasaki M, Suzuki H, Sugiyama Y. Matsushima S, et al. Among authors: maeda k. J Pharmacol Exp Ther. 2005 Sep;314(3):1059-67. doi: 10.1124/jpet.105.085589. Epub 2005 May 18. J Pharmacol Exp Ther. 2005. PMID: 15901800
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin.
Hirano M, Maeda K, Matsushima S, Nozaki Y, Kusuhara H, Sugiyama Y. Hirano M, et al. Among authors: maeda k. Mol Pharmacol. 2005 Sep;68(3):800-7. doi: 10.1124/mol.105.014019. Epub 2005 Jun 13. Mol Pharmacol. 2005. PMID: 15955871
Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.
Shimizu M, Fuse K, Okudaira K, Nishigaki R, Maeda K, Kusuhara H, Sugiyama Y. Shimizu M, et al. Among authors: maeda k. Drug Metab Dispos. 2005 Oct;33(10):1477-81. doi: 10.1124/dmd.105.004622. Epub 2005 Jul 13. Drug Metab Dispos. 2005. PMID: 16014768
Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.
Tahara H, Kusuhara H, Maeda K, Koepsell H, Fuse E, Sugiyama Y. Tahara H, et al. Among authors: maeda k. Drug Metab Dispos. 2006 May;34(5):743-7. doi: 10.1124/dmd.105.008375. Epub 2006 Feb 2. Drug Metab Dispos. 2006. PMID: 16455804
Drug-drug interaction between pitavastatin and various drugs via OATP1B1.
Hirano M, Maeda K, Shitara Y, Sugiyama Y. Hirano M, et al. Among authors: maeda k. Drug Metab Dispos. 2006 Jul;34(7):1229-36. doi: 10.1124/dmd.106.009290. Epub 2006 Apr 4. Drug Metab Dispos. 2006. PMID: 16595711
Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.
Ishiguro N, Maeda K, Kishimoto W, Saito A, Harada A, Ebner T, Roth W, Igarashi T, Sugiyama Y. Ishiguro N, et al. Among authors: maeda k. Drug Metab Dispos. 2006 Jul;34(7):1109-15. doi: 10.1124/dmd.105.009175. Epub 2006 Apr 12. Drug Metab Dispos. 2006. PMID: 16611857
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.
Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z, Sugiyama Y. Yamashiro W, et al. Among authors: maeda k. Drug Metab Dispos. 2006 Jul;34(7):1247-54. doi: 10.1124/dmd.105.008938. Epub 2006 Apr 19. Drug Metab Dispos. 2006. PMID: 16624871
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
Yamada A, Maeda K, Kamiyama E, Sugiyama D, Kondo T, Shiroyanagi Y, Nakazawa H, Okano T, Adachi M, Schuetz JD, Adachi Y, Hu Z, Kusuhara H, Sugiyama Y. Yamada A, et al. Among authors: maeda k. Drug Metab Dispos. 2007 Dec;35(12):2166-76. doi: 10.1124/dmd.107.017459. Epub 2007 Sep 6. Drug Metab Dispos. 2007. PMID: 17823233
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