Maeda K - Search Results

1

Strategies to improve the prediction accuracy of hepatic intrinsic clearance of three antidiabetic drugs: Application of the extended clearance concept and consideration of the effect of albumin on CYP2C metabolism and OATP1B-mediated hepatic uptake.

Fujino R, Hashizume K, Aoyama S, Maeda K, Ito K, Toshimoto K, Lee W, Ninomiya SI, Sugiyama Y. Fujino R, et al. Among authors: maeda k. Eur J Pharm Sci. 2018 Dec 1;125:181-192. doi: 10.1016/j.ejps.2018.09.021. Epub 2018 Oct 1. Eur J Pharm Sci. 2018. PMID: 30287410

2

pH-dependent receptor/ligand dissociation as a determining factor for intracellular sorting of ligands for epidermal growth factor receptors in rat hepatocytes.

Maeda K, Kato Y, Sugiyama Y. Maeda K, et al. J Control Release. 2002 Jul 18;82(1):71-82. doi: 10.1016/s0168-3659(02)00126-8. J Control Release. 2002. PMID: 12106978

3

Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans.

Hirano M, Maeda K, Shitara Y, Sugiyama Y. Hirano M, et al. Among authors: maeda k. J Pharmacol Exp Ther. 2004 Oct;311(1):139-46. doi: 10.1124/jpet.104.068056. Epub 2004 May 24. J Pharmacol Exp Ther. 2004. PMID: 15159445

4

Estimation of the three-dimensional pharmacophore of ligands for rat multidrug-resistance-associated protein 2 using ligand-based drug design techniques.

Hirono S, Nakagome I, Imai R, Maeda K, Kusuhara H, Sugiyama Y. Hirono S, et al. Among authors: maeda k. Pharm Res. 2005 Feb;22(2):260-9. doi: 10.1007/s01869-005-1869-8. Pharm Res. 2005. PMID: 15783074

5

Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin.

Hirano M, Maeda K, Hayashi H, Kusuhara H, Sugiyama Y. Hirano M, et al. Among authors: maeda k. J Pharmacol Exp Ther. 2005 Aug;314(2):876-82. doi: 10.1124/jpet.105.084830. Epub 2005 May 18. J Pharmacol Exp Ther. 2005. PMID: 15901796

6

Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.

Matsushima S, Maeda K, Kondo C, Hirano M, Sasaki M, Suzuki H, Sugiyama Y. Matsushima S, et al. Among authors: maeda k. J Pharmacol Exp Ther. 2005 Sep;314(3):1059-67. doi: 10.1124/jpet.105.085589. Epub 2005 May 18. J Pharmacol Exp Ther. 2005. PMID: 15901800

7

[Overview: molecular variation, specific tissue localization and genetic polymorphisms of drug transporters].

Sugiyama Y, Maeda K. Sugiyama Y, et al. Among authors: maeda k. Nihon Yakurigaku Zasshi. 2005 Apr;125(4):178-84. doi: 10.1254/fpj.125.178. Nihon Yakurigaku Zasshi. 2005. PMID: 15930793 Review. Japanese. No abstract available.

8

Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin.

Hirano M, Maeda K, Matsushima S, Nozaki Y, Kusuhara H, Sugiyama Y. Hirano M, et al. Among authors: maeda k. Mol Pharmacol. 2005 Sep;68(3):800-7. doi: 10.1124/mol.105.014019. Epub 2005 Jun 13. Mol Pharmacol. 2005. PMID: 15955871

9

Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.

Shimizu M, Fuse K, Okudaira K, Nishigaki R, Maeda K, Kusuhara H, Sugiyama Y. Shimizu M, et al. Among authors: maeda k. Drug Metab Dispos. 2005 Oct;33(10):1477-81. doi: 10.1124/dmd.105.004622. Epub 2005 Jul 13. Drug Metab Dispos. 2005. PMID: 16014768

10

Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.

Tahara H, Kusuhara H, Maeda K, Koepsell H, Fuse E, Sugiyama Y. Tahara H, et al. Among authors: maeda k. Drug Metab Dispos. 2006 May;34(5):743-7. doi: 10.1124/dmd.105.008375. Epub 2006 Feb 2. Drug Metab Dispos. 2006. PMID: 16455804

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