Maeda S - Search Results

1

Activation of the α_2B adrenoceptor by the sedative sympatholytic dexmedetomidine.

Yuan D, Liu Z, Kaindl J, Maeda S, Zhao J, Sun X, Xu J, Gmeiner P, Wang HW, Kobilka BK. Yuan D, et al. Among authors: maeda s. Nat Chem Biol. 2020 May;16(5):507-512. doi: 10.1038/s41589-020-0492-2. Epub 2020 Mar 9. Nat Chem Biol. 2020. PMID: 32152538

2

Structure of the µ-opioid receptor-G_i protein complex.

Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK. Koehl A, et al. Among authors: maeda s. Nature. 2018 Jun;558(7711):547-552. doi: 10.1038/s41586-018-0219-7. Epub 2018 Jun 13. Nature. 2018. PMID: 29899455 Free PMC article.

3

Development of an antibody fragment that stabilizes GPCR/G-protein complexes.

Maeda S, Koehl A, Matile H, Hu H, Hilger D, Schertler GFX, Manglik A, Skiniotis G, Dawson RJP, Kobilka BK. Maeda S, et al. Nat Commun. 2018 Sep 13;9(1):3712. doi: 10.1038/s41467-018-06002-w. Nat Commun. 2018. PMID: 30213947 Free PMC article.

4

Structural insights into the subtype-selective antagonist binding to the M₂ muscarinic receptor.

Suno R, Lee S, Maeda S, Yasuda S, Yamashita K, Hirata K, Horita S, Tawaramoto MS, Tsujimoto H, Murata T, Kinoshita M, Yamamoto M, Kobilka BK, Vaidehi N, Iwata S, Kobayashi T. Suno R, et al. Among authors: maeda s. Nat Chem Biol. 2018 Dec;14(12):1150-1158. doi: 10.1038/s41589-018-0152-y. Epub 2018 Nov 12. Nat Chem Biol. 2018. PMID: 30420692 Free PMC article.

5

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.

Krishna Kumar K, Shalev-Benami M, Robertson MJ, Hu H, Banister SD, Hollingsworth SA, Latorraca NR, Kato HE, Hilger D, Maeda S, Weis WI, Farrens DL, Dror RO, Malhotra SV, Kobilka BK, Skiniotis G. Krishna Kumar K, et al. Among authors: maeda s. Cell. 2019 Jan 24;176(3):448-458.e12. doi: 10.1016/j.cell.2018.11.040. Epub 2019 Jan 10. Cell. 2019. PMID: 30639101 Free PMC article.

6

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes.

Maeda S, Qu Q, Robertson MJ, Skiniotis G, Kobilka BK. Maeda S, et al. Science. 2019 May 10;364(6440):552-557. doi: 10.1126/science.aaw5188. Science. 2019. PMID: 31073061 Free PMC article.

7

Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy.

Xu J, Hu Y, Kaindl J, Risel P, Hübner H, Maeda S, Niu X, Li H, Gmeiner P, Jin C, Kobilka BK. Xu J, et al. Among authors: maeda s. Mol Cell. 2019 Jul 11;75(1):53-65.e7. doi: 10.1016/j.molcel.2019.04.028. Epub 2019 May 15. Mol Cell. 2019. PMID: 31103421 Free article.

8

Local membrane charge regulates β₂ adrenergic receptor coupling to G_i3.

Strohman MJ, Maeda S, Hilger D, Masureel M, Du Y, Kobilka BK. Strohman MJ, et al. Among authors: maeda s. Nat Commun. 2019 May 20;10(1):2234. doi: 10.1038/s41467-019-10108-0. Nat Commun. 2019. PMID: 31110175 Free PMC article.

9

Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family.

Kim HR, Xu J, Maeda S, Duc NM, Ahn D, Du Y, Chung KY. Kim HR, et al. Among authors: maeda s. Nat Commun. 2020 Jun 22;11(1):3160. doi: 10.1038/s41467-020-16975-2. Nat Commun. 2020. PMID: 32572026 Free PMC article.

10

Structure and selectivity engineering of the M₁ muscarinic receptor toxin complex.

Maeda S, Xu J, N Kadji FM, Clark MJ, Zhao J, Tsutsumi N, Aoki J, Sunahara RK, Inoue A, Garcia KC, Kobilka BK. Maeda S, et al. Science. 2020 Jul 10;369(6500):161-167. doi: 10.1126/science.aax2517. Science. 2020. PMID: 32646996 Free PMC article.

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