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Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.
Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ. Maes C, et al. EMBO J. 2010 Jan 20;29(2):424-41. doi: 10.1038/emboj.2009.361. Epub 2009 Dec 10. EMBO J. 2010. PMID: 20010698 Free PMC article.
Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism.
Dirckx N, Tower RJ, Mercken EM, Vangoitsenhoven R, Moreau-Triby C, Breugelmans T, Nefyodova E, Cardoen R, Mathieu C, Van der Schueren B, Confavreux CB, Clemens TL, Maes C. Dirckx N, et al. Among authors: maes c. J Clin Invest. 2018 Mar 1;128(3):1087-1105. doi: 10.1172/JCI97794. Epub 2018 Feb 12. J Clin Invest. 2018. PMID: 29431735 Free PMC article.
136 results