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Treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a multisystem disease, should target the pathophysiological aberrations (inflammatory and oxidative and nitrosative stress pathways), not the psychosocial "barriers" for a new equilibrium.
Maes M, Twisk FN. Maes M, et al. Patient Educ Couns. 2010 Jul;80(1):148-9; author reply 147. doi: 10.1016/j.pec.2010.02.017. Epub 2010 Mar 29. Patient Educ Couns. 2010. PMID: 20303231 No abstract available.
Multiple aberrations in shared inflammatory and oxidative & nitrosative stress (IO&NS) pathways explain the co-association of depression and cardiovascular disorder (CVD), and the increased risk for CVD and due mortality in depressed patients.
Maes M, Ruckoanich P, Chang YS, Mahanonda N, Berk M. Maes M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):769-83. doi: 10.1016/j.pnpbp.2010.06.008. Epub 2010 Jun 16. Prog Neuropsychopharmacol Biol Psychiatry. 2011. PMID: 20561554 Review.
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