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Peripheral tachykinin receptors as targets for new drugs.
Patacchini R, Maggi CA. Patacchini R, et al. Among authors: Maggi CA. Eur J Pharmacol. 2001 Oct 19;429(1-3):13-21. doi: 10.1016/s0014-2999(01)01301-2. Eur J Pharmacol. 2001. PMID: 11698023 Review.
Tachykinin autoreceptors in the gut.
Patacchini R, Maggi CA, Holzer P. Patacchini R, et al. Among authors: Maggi CA. Trends Pharmacol Sci. 2000 May;21(5):166. doi: 10.1016/s0165-6147(00)01466-8. Trends Pharmacol Sci. 2000. PMID: 10785646 No abstract available.
Different Ca2+ influx pathways mediate tachykinin receptor-induced contraction in circular muscle of guinea-pig colon.
Zagorodnyuk V, Santicioli P, Maggi CA. Zagorodnyuk V, et al. Among authors: Maggi CA. Eur J Pharmacol. 1994 Apr 1;255(1-3):9-15. doi: 10.1016/0014-2999(94)90076-0. Eur J Pharmacol. 1994. PMID: 7517885
When tested in a Ca(2+)-free medium, the contraction produced by either agonist was greatly reduced (84-89%) as compared to the control. ...These findings demonstrate that NK1 receptor-mediated contraction is strictly linked to membrane depolarization and action potentials generation through nifedipine-sensitive Ca2+ channels (electromechanical coupling) while the NK2 receptor-mediated contraction is substantially unrelated to depolarization and, while being largely dependent upon extracellular Ca2+, is nifedipine-resistant, possibly linked to the opening of non-selective (Ca(2+)-permeable) receptor-gated cation channels (pharmacomechanical coupling)....
When tested in a Ca(2+)-free medium, the contraction produced by either agonist was greatly reduced (84-89%) as compared to the contr …
Tachykinin-mediated effect of nociceptin in the rat urinary bladder in vivo.
Lecci A, Giuliani S, Tramontana M, Meini S, Santicioli P, Maggi CA. Lecci A, et al. Among authors: Maggi CA. Eur J Pharmacol. 2000 Feb 11;389(1):99-102. doi: 10.1016/s0014-2999(99)00802-x. Eur J Pharmacol. 2000. PMID: 10686301
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