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Page 1
Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.
Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, Birch J, Salmonowicz H, Ogrodnik M, Jurk D, Proctor C, Correia-Melo C, Victorelli S, Fielder E, Berlinguer-Palmini R, Owens A, Greaves LC, Kolsky KL, Parini A, Douin-Echinard V, LeBrasseur NK, Arthur HM, Tual-Chalot S, Schafer MJ, Roos CM, Miller JD, Robertson N, Mann J, Adams PD, Tchkonia T, Kirkland JL, Mialet-Perez J, Richardson GD, Passos JF. Anderson R, et al. Among authors: maggiorani d. EMBO J. 2019 Mar 1;38(5):e100492. doi: 10.15252/embj.2018100492. Epub 2019 Feb 8. EMBO J. 2019. PMID: 30737259 Free PMC article.
Clearance of defective muscle stem cells by senolytics restores myogenesis in myotonic dystrophy type 1.
Conte TC, Duran-Bishop G, Orfi Z, Mokhtari I, Deprez A, Côté I, Molina T, Kim TY, Tellier L, Roussel MP, Maggiorani D, Benabdallah B, Leclerc S, Feulner L, Pellerito O, Mathieu J, Andelfinger G, Gagnon C, Beauséjour C, McGraw S, Duchesne E, Dumont NA. Conte TC, et al. Among authors: maggiorani d. Nat Commun. 2023 Jul 19;14(1):4033. doi: 10.1038/s41467-023-39663-3. Nat Commun. 2023. PMID: 37468473 Free PMC article.
Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions.
Moquin-Beaudry G, Benabdallah B, Maggiorani D, Le O, Li Y, Colas C, Raggi C, Ellezam B, M'Callum MA, Dal Soglio D, Guimond JV, Paganelli M, Haddad E, Beauséjour C. Moquin-Beaudry G, et al. Among authors: maggiorani d. Cell Rep Methods. 2022 Jan 14;2(1):100153. doi: 10.1016/j.crmeth.2021.100153. eCollection 2022 Jan 24. Cell Rep Methods. 2022. PMID: 35474871 Free PMC article.
Kidney inflammaging is promoted by CCR2+ macrophages and tissue-derived micro-environmental factors.
Lefèvre L, Iacovoni JS, Martini H, Bellière J, Maggiorani D, Dutaur M, Marsal DJ, Decaunes P, Pizzinat N, Mialet-Perez J, Cussac D, Parini A, Douin-Echinard V. Lefèvre L, et al. Among authors: maggiorani d. Cell Mol Life Sci. 2021 Apr;78(7):3485-3501. doi: 10.1007/s00018-020-03719-0. Epub 2020 Dec 12. Cell Mol Life Sci. 2021. PMID: 33313981 Free PMC article.
Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodeling.
Santin Y, Fazal L, Sainte-Marie Y, Sicard P, Maggiorani D, Tortosa F, Yücel YY, Teyssedre L, Rouquette J, Marcellin M, Vindis C, Shih JC, Lairez O, Burlet-Schiltz O, Parini A, Lezoualc'h F, Mialet-Perez J. Santin Y, et al. Among authors: maggiorani d. Cell Death Differ. 2020 Jun;27(6):1907-1923. doi: 10.1038/s41418-019-0470-y. Epub 2019 Dec 9. Cell Death Differ. 2020. PMID: 31819159 Free PMC article.
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