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Consensus statement on chronic and subacute high altitude diseases.
León-Velarde F, Maggiorini M, Reeves JT, Aldashev A, Asmus I, Bernardi L, Ge RL, Hackett P, Kobayashi T, Moore LG, Penaloza D, Richalet JP, Roach R, Wu T, Vargas E, Zubieta-Castillo G, Zubieta-Calleja G. León-Velarde F, et al. Among authors: Maggiorini M. High Alt Med Biol. 2005 Summer;6(2):147-57. doi: 10.1089/ham.2005.6.147. High Alt Med Biol. 2005. PMID: 16060849 Review.
These guidelines are established to inform the medical services on site who are directed to solve high altitude health problems about the definition, diagnosis, treatment, and prevention of the most common chronic high altitude diseases. ...Most of the cases of high …
These guidelines are established to inform the medical services on site who are directed to solve high altitude health problems about …
Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions: A joint statement by the European Society of Cardiology, the Council on Hypertension of the European Society of Cardiology, the European Society of Hypertension, the International Society of Mountain Medicine, the Italian Society of Hypertension and the Italian Society of Mountain Medicine.
Parati G, Agostoni P, Basnyat B, Bilo G, Brugger H, Coca A, Festi L, Giardini G, Lironcurti A, Luks AM, Maggiorini M, Modesti PA, Swenson ER, Williams B, Bärtsch P, Torlasco C. Parati G, et al. Among authors: Maggiorini M. Eur Heart J. 2018 May 1;39(17):1546-1554. doi: 10.1093/eurheartj/ehx720. Eur Heart J. 2018. PMID: 29340578 Free PMC article. Review.
The 2018 Lake Louise Acute Mountain Sickness Score.
Roach RC, Hackett PH, Oelz O, Bärtsch P, Luks AM, MacInnis MJ, Baillie JK; Lake Louise AMS Score Consensus Committee. Roach RC, et al. High Alt Med Biol. 2018 Mar;19(1):4-6. doi: 10.1089/ham.2017.0164. Epub 2018 Mar 13. High Alt Med Biol. 2018. PMID: 29583031 Free PMC article.
Recent studies have shown that disturbed sleep at altitude, one of the five symptoms scored for AMS, is more likely due to altitude hypoxia per se, and is not closely related to AMS. To address this issue, and also to evaluate the Lake Louise AMS score in light of d …
Recent studies have shown that disturbed sleep at altitude, one of the five symptoms scored for AMS, is more likely due to altitud
Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude.
Fruehauf H, Vavricka SR, Lutz TA, Gassmann M, Wojtal KA, Erb A, Maggiorini M, Schwizer W, Fried M, Fox M, Goetze O, Greuter T. Fruehauf H, et al. Among authors: Maggiorini M. Clin Gastroenterol Hepatol. 2019 Nov 25:S1542-3565(19)31324-2. doi: 10.1016/j.cgh.2019.11.036. Online ahead of print. Clin Gastroenterol Hepatol. 2019. PMID: 31778804
BACKGROUND & AIMS: It is not clear how rapid ascent to a high altitude causes the gastrointestinal symptoms of acute mountain sickness (AMS). ...RESULTS: The follow-up endoscopy at high altitude was performed in 19 of 25 patients on day 2 and in 23 of 25 patient …
BACKGROUND & AIMS: It is not clear how rapid ascent to a high altitude causes the gastrointestinal symptoms of acute mountain sic …
Recruitment of non-perfused sublingual capillaries increases microcirculatory oxygen extraction capacity throughout ascent to 7126 m.
Hilty MP, Merz TM, Hefti U, Ince C, Maggiorini M, Pichler Hefti J. Hilty MP, et al. Among authors: Maggiorini M. J Physiol. 2019 May;597(10):2623-2638. doi: 10.1113/JP277590. Epub 2019 Mar 28. J Physiol. 2019. PMID: 30843200 Free PMC article.
KEY POINTS: A physiological response to increase microcirculatory oxygen extraction capacity at high altitude is to recruit capillaries. ...ABSTRACT: A high altitude (HA) stay is associated with an increase in sublingual capillary total vessel density (TVD), suggest …
KEY POINTS: A physiological response to increase microcirculatory oxygen extraction capacity at high altitude is to recruit capillari …
The STAR Data Reporting Guidelines for Clinical High Altitude Research.
Brodmann Maeder M, Brugger H, Pun M, Strapazzon G, Dal Cappello T, Maggiorini M, Hackett P, Bärtsch P, Swenson ER, Zafren K. Brodmann Maeder M, et al. Among authors: Maggiorini M. High Alt Med Biol. 2018 Mar;19(1):7-14. doi: 10.1089/ham.2017.0160. Epub 2018 Feb 9. High Alt Med Biol. 2018. PMID: 29596018 Free PMC article.
The STARdata reporting guidelines for clinical high altitude research. High AltMedBiol. 19:7-14, 2018. AIMS: The goal of the STAR (STrengthening Altitude Research) initiative was to produce a uniform set of key elements for research and reporting in clinical high- …
The STARdata reporting guidelines for clinical high altitude research. High AltMedBiol. 19:7-14, 2018. AIMS: The goal of the STAR (ST …
Effect of Increased Blood Flow on Pulmonary Circulation Before and During High Altitude Acclimatization.
Hilty MP, Müller A, Flück D, Siebenmann C, Rasmussen P, Keiser S, Auinger K, Lundby C, Maggiorini M. Hilty MP, et al. Among authors: Maggiorini M. High Alt Med Biol. 2016 Dec;17(4):305-314. doi: 10.1089/ham.2016.0004. Epub 2016 Oct 18. High Alt Med Biol. 2016. PMID: 27754698
Effect of increased blood flow on the pulmonary circulation before and during high altitude acclimatization. High Alt Med Biol. 17:305-314, 2016.-Introduction and Methods: Acute exposure to high altitude increases pulmonary artery pressure (Ppa) and pulmonary vascul …
Effect of increased blood flow on the pulmonary circulation before and during high altitude acclimatization. High Alt Med Biol. 17:30 …
Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude.
Siebenmann C, Rasmussen P, Hug M, Keiser S, Flück D, Fisher JP, Hilty MP, Maggiorini M, Lundby C. Siebenmann C, et al. Among authors: Maggiorini M. J Physiol. 2017 Mar 1;595(5):1619-1626. doi: 10.1113/JP273726. Epub 2017 Jan 24. J Physiol. 2017. PMID: 27966225 Free PMC article. Clinical Trial.
In seven lowlanders, heart rate was measured at sea level and after 2 weeks at high altitude after individual and combined pharmacological inhibition of sympathetic and/or parasympathetic control of the heart. Inhibition of parasympathetic control of the heart alone or in …
In seven lowlanders, heart rate was measured at sea level and after 2 weeks at high altitude after individual and combined pharmacolo …
Effect of ascent protocol on acute mountain sickness and success at Muztagh Ata, 7546 m.
Bloch KE, Turk AJ, Maggiorini M, Hess T, Merz T, Bosch MM, Barthelmes D, Hefti U, Pichler J, Senn O, Schoch OD. Bloch KE, et al. Among authors: Maggiorini M. High Alt Med Biol. 2009 Spring;10(1):25-32. doi: 10.1089/ham.2008.1043. High Alt Med Biol. 2009. PMID: 19326598 Clinical Trial.
We performed a randomized, controlled trial during a high altitude medical research expedition to Muztagh Ata. Thirty-four healthy mountaineers (mean age 45 yr, 7 women) were randomized to follow one of two protocols, ascending within 15 or 19 days to the summit of Muztagh …
We performed a randomized, controlled trial during a high altitude medical research expedition to Muztagh Ata. Thirty-four healthy mo …
High altitude-induced pulmonary oedema.
Maggiorini M. Maggiorini M. Cardiovasc Res. 2006 Oct 1;72(1):41-50. doi: 10.1016/j.cardiores.2006.07.004. Epub 2006 Jul 12. Cardiovasc Res. 2006. PMID: 16904089 Review.
Almost one mountain trekker or climber out of two develops several symptoms of high altitude illness after a rapid ascent (> 300 m/day) to an altitude above 4000 m. ...Susceptible individuals can prevent HAPE by slow ascent: an average gain of altitude not …
Almost one mountain trekker or climber out of two develops several symptoms of high altitude illness after a rapid ascent (> 300 m …
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