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22 results

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Page 1
Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism.
Magnotti F, Chirita D, Dalmon S, Martin A, Bronnec P, Sousa J, Helynck O, Lee W, Kastner DL, Chae JJ, McDermott MF, Belot A, Popoff M, Sève P, Georgin-Lavialle S, Munier-Lehmann H, Tran TA, De Langhe E, Wouters C, Jamilloux Y, Henry T. Magnotti F, et al. Cell Rep. 2022 Oct 11;41(2):111472. doi: 10.1016/j.celrep.2022.111472. Cell Rep. 2022. PMID: 36223753 Free PMC article.
Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients.
Magnotti F, Lefeuvre L, Benezech S, Malsot T, Waeckel L, Martin A, Kerever S, Chirita D, Desjonqueres M, Duquesne A, Gerfaud-Valentin M, Laurent A, Sève P, Popoff MR, Walzer T, Belot A, Jamilloux Y, Henry T. Magnotti F, et al. EMBO Mol Med. 2019 Nov 7;11(11):e10547. doi: 10.15252/emmm.201910547. Epub 2019 Oct 7. EMBO Mol Med. 2019. PMID: 31589380 Free PMC article.
Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome.
Jamilloux Y, Lefeuvre L, Magnotti F, Martin A, Benezech S, Allatif O, Penel-Page M, Hentgen V, Sève P, Gerfaud-Valentin M, Duquesne A, Desjonquères M, Laurent A, Rémy-Piccolo V, Cimaz R, Cantarini L, Bourdonnay E, Walzer T, Py BF, Belot A, Henry T. Jamilloux Y, et al. Among authors: magnotti f. Rheumatology (Oxford). 2018 Jan 1;57(1):100-111. doi: 10.1093/rheumatology/kex373. Rheumatology (Oxford). 2018. PMID: 29040788
Fast diagnostic test for familial Mediterranean fever based on a kinase inhibitor.
Magnotti F, Malsot T, Georgin-Lavialle S, Abbas F, Martin A, Belot A, Fauter M, Rabilloud M, Gerfaud-Valentin M, Sève P, Duquesne A, Hot A, Durupt S, Savey L, Giurgea I, Grateau G, Henry T, Jamilloux Y. Magnotti F, et al. Ann Rheum Dis. 2021 Jan;80(1):128-132. doi: 10.1136/annrheumdis-2020-218366. Epub 2020 Oct 9. Ann Rheum Dis. 2021. PMID: 33037005
LACC1 deficiency links juvenile arthritis with autophagy and metabolism in macrophages.
Omarjee O, Mathieu AL, Quiniou G, Moreews M, Ainouze M, Frachette C, Melki I, Dumaine C, Gerfaud-Valentin M, Duquesne A, Kallinich T, Tahir Turanli E, Malcus C, Viel S, Pescarmona R, Georgin-Lavialle S, Jamilloux Y, Larbre JP, Sarrabay G, Magnotti F, Rice GI, Bleicher F, Reboulet J, Merabet S, Henry T, Crow YJ, Faure M, Walzer T, Belot A. Omarjee O, et al. Among authors: magnotti f. J Exp Med. 2021 Mar 1;218(3):e20201006. doi: 10.1084/jem.20201006. J Exp Med. 2021. PMID: 33606008 Free PMC article.
22 results