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Danger signals in stroke.
Gelderblom M, Sobey CG, Kleinschnitz C, Magnus T. Gelderblom M, et al. Among authors: Magnus T. Ageing Res Rev. 2015 Nov;24(Pt A):77-82. doi: 10.1016/j.arr.2015.07.004. Epub 2015 Jul 22. Ageing Res Rev. 2015. PMID: 26210897 Review.
γδ T cells as early sensors of tissue damage and mediators of secondary neurodegeneration.
Gelderblom M, Arunachalam P, Magnus T. Gelderblom M, et al. Among authors: Magnus T. Front Cell Neurosci. 2014 Nov 5;8:368. doi: 10.3389/fncel.2014.00368. eCollection 2014. Front Cell Neurosci. 2014. PMID: 25414640 Free PMC article. Review.
Recently, T cells have been shown to be an essential part of the post-ischemic tissue damage, and especially IL-17 secreting T cells have been implicated in the pathogenesis of a variety of inflammatory reactions in the brain. After stroke, it seems that the innate …
Recently, T cells have been shown to be an essential part of the post-ischemic tissue damage, and especially IL-17 secreting T
In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells.
Rissiek B, Lukowiak M, Raczkowski F, Magnus T, Mittrücker HW, Koch-Nolte F. Rissiek B, et al. Among authors: Magnus T. Front Immunol. 2018 Jul 9;9:1580. doi: 10.3389/fimmu.2018.01580. eCollection 2018. Front Immunol. 2018. PMID: 30038627 Free PMC article.
We have previously shown that chronic gating of P2X7 by ADP-ribosylation reduces the vitality and function of regulatory T cells and natural killer T cells that co-express high levels of ARTC2.2 and P2X7. Here, we evaluated the expression of ARTC2.2 and P2X7 by effe …
We have previously shown that chronic gating of P2X7 by ADP-ribosylation reduces the vitality and function of regulatory T cells and …
Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia.
Adesso S, Magnus T, Cuzzocrea S, Campolo M, Rissiek B, Paciello O, Autore G, Pinto A, Marzocco S. Adesso S, et al. Among authors: Magnus T. Front Pharmacol. 2017 Jun 12;8:370. doi: 10.3389/fphar.2017.00370. eCollection 2017. Front Pharmacol. 2017. PMID: 28659803 Free PMC article.
Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury.
Thom V, Arumugam TV, Magnus T, Gelderblom M. Thom V, et al. Among authors: Magnus T. Front Immunol. 2017 Jul 31;8:875. doi: 10.3389/fimmu.2017.00875. eCollection 2017. Front Immunol. 2017. PMID: 28824617 Free PMC article. Review.
Autoimmunity After Ischemic Stroke and Brain Injury.
Javidi E, Magnus T. Javidi E, et al. Among authors: Magnus T. Front Immunol. 2019 Apr 2;10:686. doi: 10.3389/fimmu.2019.00686. eCollection 2019. Front Immunol. 2019. PMID: 31001280 Free PMC article. Review.
In stroke patients, the detection of T cells and antibodies specific to neuronal antigens suggests a role of humoral adaptive immunity. ...In this review, we will summarize the role of autoimmunity in post-lesional conditions and discuss the role of B and T cells an …
In stroke patients, the detection of T cells and antibodies specific to neuronal antigens suggests a role of humoral adaptive immunit …
Quantitative T2* mapping reveals early temporo-spatial dynamics in an ischemic stroke model.
Gersing AS, Faymonville AM, Schwaiger BJ, Leypoldt F, Siemonsen S, Zimmer C, Magnus T, Fiehler J. Gersing AS, et al. Among authors: Magnus T. J Neurosci Methods. 2016 Feb 1;259:83-89. doi: 10.1016/j.jneumeth.2015.11.018. Epub 2015 Nov 29. J Neurosci Methods. 2016. PMID: 26645798
Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.
Danquah W, Meyer-Schwesinger C, Rissiek B, Pinto C, Serracant-Prat A, Amadi M, Iacenda D, Knop JH, Hammel A, Bergmann P, Schwarz N, Assunção J, Rotthier W, Haag F, Tolosa E, Bannas P, Boué-Grabot E, Magnus T, Laeremans T, Stortelers C, Koch-Nolte F. Danquah W, et al. Among authors: Magnus T. Sci Transl Med. 2016 Nov 23;8(366):366ra162. doi: 10.1126/scitranslmed.aaf8463. Sci Transl Med. 2016. PMID: 27881823
Systemic injection of nanobody 13A7 in mice blocked P2X7 on T cells and macrophages in vivo and ameliorated experimental glomerulonephritis and allergic contact dermatitis. ...
Systemic injection of nanobody 13A7 in mice blocked P2X7 on T cells and macrophages in vivo and ameliorated experimental glomerulonep …
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