Magnuson MA - Search Results

1

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.

Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: magnuson ma. Nat Genet. 2002 May;31(1):111-5. doi: 10.1038/ng872. Epub 2002 Apr 1. Nat Genet. 2002. PMID: 11923875

2

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: magnuson ma. Cell. 1999 Feb 5;96(3):329-39. doi: 10.1016/s0092-8674(00)80546-2. Cell. 1999. PMID: 10025399 Free article.

3

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction.

Michael MD, Kulkarni RN, Postic C, Previs SF, Shulman GI, Magnuson MA, Kahn CR. Michael MD, et al. Among authors: magnuson ma. Mol Cell. 2000 Jul;6(1):87-97. Mol Cell. 2000. PMID: 10949030 Free article.

4

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

Silva JP, Köhler M, Graff C, Oldfors A, Magnuson MA, Berggren PO, Larsson NG. Silva JP, et al. Among authors: magnuson ma. Nat Genet. 2000 Nov;26(3):336-40. doi: 10.1038/81649. Nat Genet. 2000. PMID: 11062475

5

Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis.

Rosen ED, Kulkarni RN, Sarraf P, Ozcan U, Okada T, Hsu CH, Eisenman D, Magnuson MA, Gonzalez FJ, Kahn CR, Spiegelman BM. Rosen ED, et al. Among authors: magnuson ma. Mol Cell Biol. 2003 Oct;23(20):7222-9. doi: 10.1128/MCB.23.20.7222-7229.2003. Mol Cell Biol. 2003. PMID: 14517292 Free PMC article.

6

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

Matschinsky FM, Glaser B, Magnuson MA. Matschinsky FM, et al. Among authors: magnuson ma. Diabetes. 1998 Mar;47(3):307-15. doi: 10.2337/diabetes.47.3.307. Diabetes. 1998. PMID: 9519733 Review.

7

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia.

Sund NJ, Vatamaniuk MZ, Casey M, Ang SL, Magnuson MA, Stoffers DA, Matschinsky FM, Kaestner KH. Sund NJ, et al. Among authors: magnuson ma. Genes Dev. 2001 Jul 1;15(13):1706-15. doi: 10.1101/gad.901601. Genes Dev. 2001. PMID: 11445544 Free PMC article.

8

Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine.

Doliba NM, Qin W, Vatamaniuk MZ, Li C, Zelent D, Najafi H, Buettger CW, Collins HW, Carr RD, Magnuson MA, Matschinsky FM. Doliba NM, et al. Among authors: magnuson ma. Am J Physiol Endocrinol Metab. 2004 May;286(5):E834-43. doi: 10.1152/ajpendo.00292.2003. Epub 2004 Jan 21. Am J Physiol Endocrinol Metab. 2004. PMID: 14736703 Free article.

9

Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass.

Roccisana J, Reddy V, Vasavada RC, Gonzalez-Pertusa JA, Magnuson MA, Garcia-Ocaña A. Roccisana J, et al. Among authors: magnuson ma. Diabetes. 2005 Jul;54(7):2090-102. doi: 10.2337/diabetes.54.7.2090. Diabetes. 2005. PMID: 15983210

10

pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.

Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV. Gannon M, et al. Among authors: magnuson ma. Dev Biol. 2008 Feb 15;314(2):406-17. doi: 10.1016/j.ydbio.2007.10.038. Epub 2007 Nov 4. Dev Biol. 2008. PMID: 18155690 Free PMC article.

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