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Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion.
Battaglia S, Maguire O, Thorne JL, Hornung LB, Doig CL, Liu S, Sucheston LE, Bianchi A, Khanim FL, Gommersall LM, Coulter HS, Rakha S, Giddings I, O'Neill LP, Cooper CS, McCabe CJ, Bunce CM, Campbell MJ. Battaglia S, et al. Among authors: maguire o, o neill lp. Carcinogenesis. 2010 Sep;31(9):1650-60. doi: 10.1093/carcin/bgq086. Epub 2010 May 13. Carcinogenesis. 2010. PMID: 20466759 Free PMC article.
Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells.
Thorne JL, Maguire O, Doig CL, Battaglia S, Fehr L, Sucheston LE, Heinaniemi M, O'Neill LP, McCabe CJ, Turner BM, Carlberg C, Campbell MJ. Thorne JL, et al. Among authors: maguire o, o neill lp. Nucleic Acids Res. 2011 Mar;39(6):2045-56. doi: 10.1093/nar/gkq875. Epub 2010 Nov 17. Nucleic Acids Res. 2011. PMID: 21088000 Free PMC article.
Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns.
Doig CL, Singh PK, Dhiman VK, Thorne JL, Battaglia S, Sobolewski M, Maguire O, O'Neill LP, Turner BM, McCabe CJ, Smiraglia DJ, Campbell MJ. Doig CL, et al. Among authors: maguire o, o neill lp. Carcinogenesis. 2013 Feb;34(2):248-56. doi: 10.1093/carcin/bgs331. Epub 2012 Oct 20. Carcinogenesis. 2013. PMID: 23087083 Free PMC article.
Publisher Correction: Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment.
Shu S, Yang Y, Allen CL, Maguire O, Minderman H, Sen A, Ciesielski MJ, Collins KA, Bush PJ, Singh P, Wang X, Morgan M, Qu J, Bankert RB, Whiteside TL, Wu Y, Ernstoff MS. Shu S, et al. Among authors: maguire o. Sci Rep. 2019 Mar 15;9(1):4959. doi: 10.1038/s41598-018-37179-1. Sci Rep. 2019. PMID: 30874569 Free PMC article.
Multicenter phase 2 trial of nintedanib in advanced nonpancreatic neuroendocrine tumors.
Iyer RV, Konda B, Fountzilas C, Mukherjee S, Owen D, Attwood K, Wang C, Maguire O, Minderman H, Suffren SA, Hicks K, Wilton J, Bies R, Casucci D, Reidy-Lagunes D, Shah M. Iyer RV, et al. Among authors: maguire o. Cancer. 2020 Aug 15;126(16):3689-3697. doi: 10.1002/cncr.32994. Epub 2020 Jun 11. Cancer. 2020. PMID: 32525561 Free PMC article. Clinical Trial.
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