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Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547.
Cancer Res. 2018 Oct 1;78(19):5668-5679. doi: 10.1158/0008-5472.CAN-18-0757. Epub 2018 Aug 16.
Cancer Res. 2018.
PMID: 30115694
ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.
Jansen RS, Mahakena S, de Haas M, Borst P, van de Wetering K.
Jansen RS, et al. Among authors: mahakena s.
J Biol Chem. 2015 Dec 18;290(51):30429-40. doi: 10.1074/jbc.M115.692103. Epub 2015 Oct 29.
J Biol Chem. 2015.
PMID: 26515061
Free PMC article.
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MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum.
Rijpma SR, van der Velden M, Bilos A, Jansen RS, Mahakena S, Russel FG, Sauerwein RW, van de Wetering K, Koenderink JB.
Rijpma SR, et al. Among authors: mahakena s.
FEBS Lett. 2016 Feb;590(4):482-92. doi: 10.1002/1873-3468.12079. Epub 2016 Feb 17.
FEBS Lett. 2016.
PMID: 26900081
Free article.
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ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.
Jansen RS, Duijst S, Mahakena S, Sommer D, Szeri F, Váradi A, Plomp A, Bergen AA, Oude Elferink RP, Borst P, van de Wetering K.
Jansen RS, et al. Among authors: mahakena s.
Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1985-9. doi: 10.1161/ATVBAHA.114.304017. Epub 2014 Jun 26.
Arterioscler Thromb Vasc Biol. 2014.
PMID: 24969777
Free PMC article.
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N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids.
Jansen RS, Addie R, Merkx R, Fish A, Mahakena S, Bleijerveld OB, Altelaar M, IJlst L, Wanders RJ, Borst P, van de Wetering K.
Jansen RS, et al. Among authors: mahakena s.
Proc Natl Acad Sci U S A. 2015 May 26;112(21):6601-6. doi: 10.1073/pnas.1424638112. Epub 2015 May 11.
Proc Natl Acad Sci U S A. 2015.
PMID: 25964343
Free PMC article.
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Impact of chemistry and nanoformulation parameters on cellular uptake and airway distribution of RNA oligonucleotides.
Oude Blenke E, Mahakena S, Fens M, van den Dikkenberg J, Holkers M, Mastrobattista E.
Oude Blenke E, et al. Among authors: mahakena s.
J Control Release. 2020 Jan 10;317:154-165. doi: 10.1016/j.jconrel.2019.11.025. Epub 2019 Nov 22.
J Control Release. 2020.
PMID: 31765703
Free article.
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