Mahindroo N - Search Results

1

Indole-2-amide based biochemical antagonist of Dishevelled PDZ domain interaction down-regulates Dishevelled-driven Tcf transcriptional activity.

Mahindroo N, Punchihewa C, Bail AM, Fujii N. Mahindroo N, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):946-9. doi: 10.1016/j.bmcl.2007.12.039. Epub 2007 Dec 23. Bioorg Med Chem Lett. 2008. PMID: 18180158

2

Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains.

Mayasundari A, Ferreira AM, He L, Mahindroo N, Bashford D, Fujii N. Mayasundari A, et al. Among authors: mahindroo n. Bioorg Med Chem Lett. 2008 Feb 1;18(3):942-5. doi: 10.1016/j.bmcl.2007.12.038. Epub 2007 Dec 23. Bioorg Med Chem Lett. 2008. PMID: 18180157

3

Hedgehog-Gli signaling pathway inhibitors as anticancer agents.

Mahindroo N, Punchihewa C, Fujii N. Mahindroo N, et al. J Med Chem. 2009 Jul 9;52(13):3829-45. doi: 10.1021/jm801420y. J Med Chem. 2009. PMID: 19309080 Free PMC article. Review. No abstract available.

4

Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription.

Mahindroo N, Connelly MC, Punchihewa C, Kimura H, Smeltzer MP, Wu S, Fujii N. Mahindroo N, et al. J Med Chem. 2009 Jul 23;52(14):4277-87. doi: 10.1021/jm900106f. J Med Chem. 2009. PMID: 19545120 Free PMC article.

5

Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway.

Mahindroo N, Connelly MC, Punchihewa C, Yang L, Yan B, Fujii N. Mahindroo N, et al. Bioorg Med Chem. 2010 Jul 1;18(13):4801-11. doi: 10.1016/j.bmc.2010.05.001. Epub 2010 May 7. Bioorg Med Chem. 2010. PMID: 20605720 Free PMC article.

6

Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: design, synthesis, structural biology, and molecular docking studies.

Mahindroo N, Wang CC, Liao CC, Huang CF, Lu IL, Lien TW, Peng YH, Huang WJ, Lin YT, Hsu MC, Lin CH, Tsai CH, Hsu JT, Chen X, Lyu PC, Chao YS, Wu SY, Hsieh HP. Mahindroo N, et al. J Med Chem. 2006 Feb 9;49(3):1212-6. doi: 10.1021/jm0510373. J Med Chem. 2006. PMID: 16451087

7

Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents.

Hsieh HP, Liou JP, Lin YT, Mahindroo N, Chang JY, Yang YN, Chern SS, Tan UK, Chang CW, Chen TW, Lin CH, Chang YY, Wang CC. Hsieh HP, et al. Among authors: mahindroo n. Bioorg Med Chem Lett. 2003 Jan 6;13(1):101-5. doi: 10.1016/s0960-894x(02)00850-8. Bioorg Med Chem Lett. 2003. PMID: 12467626

8

Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities.

Mahindroo N, Huang CF, Peng YH, Wang CC, Liao CC, Lien TW, Chittimalla SK, Huang WJ, Chai CH, Prakash E, Chen CP, Hsu TA, Peng CH, Lu IL, Lee LH, Chang YW, Chen WC, Chou YC, Chen CT, Goparaju CM, Chen YS, Lan SJ, Yu MC, Chen X, Chao YS, Wu SY, Hsieh HP. Mahindroo N, et al. J Med Chem. 2005 Dec 29;48(26):8194-208. doi: 10.1021/jm0506930. J Med Chem. 2005. PMID: 16366601

9

Identification of antimalarial leads with dual falcipain-2 and falcipain-3 inhibitory activity.

Rana D, Kalamuddin M, Sundriyal S, Jaiswal V, Sharma G, Das Sarma K, Sijwali PS, Mohmmed A, Malhotra P, Mahindroo N. Rana D, et al. Among authors: mahindroo n. Bioorg Med Chem. 2020 Jan 1;28(1):115155. doi: 10.1016/j.bmc.2019.115155. Epub 2019 Nov 9. Bioorg Med Chem. 2020. PMID: 31744777

10

Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.

Lu IL, Mahindroo N, Liang PH, Peng YH, Kuo CJ, Tsai KC, Hsieh HP, Chao YS, Wu SY. Lu IL, et al. Among authors: mahindroo n. J Med Chem. 2006 Aug 24;49(17):5154-61. doi: 10.1021/jm060207o. J Med Chem. 2006. PMID: 16913704

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