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Melatonin in patients with reduced REM sleep duration: two randomized controlled trials.
Kunz D, Mahlberg R, Müller C, Tilmann A, Bes F. Kunz D, et al. Among authors: mahlberg r. J Clin Endocrinol Metab. 2004 Jan;89(1):128-34. doi: 10.1210/jc.2002-021057. J Clin Endocrinol Metab. 2004. PMID: 14715839 Clinical Trial.
Effects of rivastigmine on actigraphically monitored motor activity in severe agitation related to Alzheimer's disease: a placebo-controlled pilot study.
Mahlberg R, Walther S, Eichmann U, Tracik F, Kunz D. Mahlberg R, et al. Arch Gerontol Geriatr. 2007 Jul-Aug;45(1):19-26. doi: 10.1016/j.archger.2006.07.006. Epub 2006 Sep 11. Arch Gerontol Geriatr. 2007. PMID: 16963137 Clinical Trial.
Degree of pineal calcification (DOC) is associated with polysomnographic sleep measures in primary insomnia patients.
Mahlberg R, Kienast T, Hädel S, Heidenreich JO, Schmitz S, Kunz D. Mahlberg R, et al. Sleep Med. 2009 Apr;10(4):439-45. doi: 10.1016/j.sleep.2008.05.003. Epub 2008 Aug 27. Sleep Med. 2009. PMID: 18755628
RESULTS: UPT was positively associated with 24-h aMT6s excretion (r=0.569; P=0.002), but CPT was not. After controlling for age, aMT6s parameters, CPT, and UPT did not correlate with any of the PSG parameters evaluated. In contrast, DOC was negatively associated with REM s …
RESULTS: UPT was positively associated with 24-h aMT6s excretion (r=0.569; P=0.002), but CPT was not. After controlling for age, aMT6 …
Melatonin excretion levels and polysomnographic sleep parameters in healthy subjects and patients with sleep-related disturbances.
Mahlberg R, Kunz D. Mahlberg R, et al. Sleep Med. 2007 Aug;8(5):512-6. doi: 10.1016/j.sleep.2006.11.001. Epub 2007 Jun 19. Sleep Med. 2007. PMID: 17581781
Normative data on the daily profile of urinary 6-sulfatoxymelatonin in healthy subjects between the ages of 20 and 84.
Mahlberg R, Tilmann A, Salewski L, Kunz D. Mahlberg R, et al. Psychoneuroendocrinology. 2006 Jun;31(5):634-41. doi: 10.1016/j.psyneuen.2006.01.009. Epub 2006 Apr 3. Psychoneuroendocrinology. 2006. PMID: 16584848
Twenty-four hour-aMT6s total amount (rho=-0.68, p<0.001), aMT6s nighttime excretion (rho=-0.69, p<0.001), aMT6s morning excretion (rho=-0.66, p<0.001) and evening excretion (r=-0.26, p=0.023) were negatively associated with age, whereas daytime excretion (r
Twenty-four hour-aMT6s total amount (rho=-0.68, p<0.001), aMT6s nighttime excretion (rho=-0.69, p<0.001), aMT6s morning excretion (rho …
Pineal calcification in Alzheimer's disease: an in vivo study using computed tomography.
Mahlberg R, Walther S, Kalus P, Bohner G, Haedel S, Reischies FM, Kühl KP, Hellweg R, Kunz D. Mahlberg R, et al. Neurobiol Aging. 2008 Feb;29(2):203-9. doi: 10.1016/j.neurobiolaging.2006.10.003. Epub 2006 Nov 13. Neurobiol Aging. 2008. PMID: 17097768
Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia.
Walther S, Mahlberg R, Eichmann U, Kunz D. Walther S, et al. Among authors: mahlberg r. Psychopharmacology (Berl). 2006 May;185(4):524-8. doi: 10.1007/s00213-006-0343-1. Epub 2006 Mar 7. Psychopharmacology (Berl). 2006. PMID: 16521031 Clinical Trial.
A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.
Kunz D, Mahlberg R. Kunz D, et al. Among authors: mahlberg r. J Sleep Res. 2010 Dec;19(4):591-6. doi: 10.1111/j.1365-2869.2010.00848.x. J Sleep Res. 2010. PMID: 20561180 Clinical Trial.
A new concept for melatonin deficit: on pineal calcification and melatonin excretion.
Kunz D, Schmitz S, Mahlberg R, Mohr A, Stöter C, Wolf KJ, Herrmann WM. Kunz D, et al. Among authors: mahlberg r. Neuropsychopharmacology. 1999 Dec;21(6):765-72. doi: 10.1016/S0893-133X(99)00069-X. Neuropsychopharmacology. 1999. PMID: 10633482
Computed tomography of the human pineal gland for study of the sleep-wake rhythm: reproducibility of a semi-quantitative approach.
Schmitz SA, Platzek I, Kunz D, Mahlberg R, Wolf KJ, Heidenreich JO. Schmitz SA, et al. Among authors: mahlberg r. Acta Radiol. 2006 Oct;47(8):865-71. doi: 10.1080/02841850600827585. Acta Radiol. 2006. PMID: 17050369
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