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Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapse.
Mahyar-Roemer M, Katsen A, Mestres P, Roemer K. Mahyar-Roemer M, et al. Int J Cancer. 2001 Dec 1;94(5):615-22. doi: 10.1002/ijc.1516. Int J Cancer. 2001. PMID: 11745454 Free article.
Bax and Bak are the critical complementary effectors of colorectal cancer cell apoptosis by chemopreventive resveratrol.
Pöhland T, Wagner S, Mahyar-Roemer M, Roemer K. Pöhland T, et al. Among authors: mahyar roemer m. Anticancer Drugs. 2006 Apr;17(4):471-8. doi: 10.1097/01.cad.0000203387.29916.8e. Anticancer Drugs. 2006. PMID: 16550006
Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells.
Mahyar-Roemer M, Fritzsche C, Wagner S, Laue M, Roemer K. Mahyar-Roemer M, et al. Oncogene. 2004 Aug 19;23(37):6226-36. doi: 10.1038/sj.onc.1207637. Oncogene. 2004. PMID: 15247902 Free article.
Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.
Mahyar-Roemer M, Köhler H, Roemer K. Mahyar-Roemer M, et al. BMC Cancer. 2002 Oct 17;2:27. doi: 10.1186/1471-2407-2-27. BMC Cancer. 2002. PMID: 12383351 Free PMC article.
The basis for the chemopreventive action of resveratrol.
Roemer K, Mahyar-Roemer M. Roemer K, et al. Among authors: mahyar roemer m. Drugs Today (Barc). 2002 Aug;38(8):571-80. doi: 10.1358/dot.2002.38.8.820097. Drugs Today (Barc). 2002. PMID: 12582422 Review.
Identification of a putative p53 binding sequence within the human mitochondrial genome.
Heyne K, Mannebach S, Wuertz E, Knaup KX, Mahyar-Roemer M, Roemer K. Heyne K, et al. Among authors: mahyar roemer m. FEBS Lett. 2004 Dec 3;578(1-2):198-202. doi: 10.1016/j.febslet.2004.10.099. FEBS Lett. 2004. PMID: 15581641 Free article.
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
Mahyar-Roemer M, Roemer K. Mahyar-Roemer M, et al. Oncogene. 2001 Jun 7;20(26):3387-98. doi: 10.1038/sj.onc.1204440. Oncogene. 2001. PMID: 11423989 Free article.
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