Maier DL - Search Results

1

F-18 Polyethyleneglycol stilbenes as PET imaging agents targeting Abeta aggregates in the brain.

Zhang W, Oya S, Kung MP, Hou C, Maier DL, Kung HF. Zhang W, et al. Among authors: maier dl. Nucl Med Biol. 2005 Nov;32(8):799-809. doi: 10.1016/j.nucmedbio.2005.06.001. Nucl Med Biol. 2005. PMID: 16253804

2

Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice.

Kung MP, Hou C, Zhuang ZP, Cross AJ, Maier DL, Kung HF. Kung MP, et al. Among authors: maier dl. Eur J Nucl Med Mol Imaging. 2004 Aug;31(8):1136-45. doi: 10.1007/s00259-004-1487-z. Epub 2004 Mar 9. Eur J Nucl Med Mol Imaging. 2004. PMID: 15007564

3

F-18 stilbenes as PET imaging agents for detecting beta-amyloid plaques in the brain.

Zhang W, Oya S, Kung MP, Hou C, Maier DL, Kung HF. Zhang W, et al. Among authors: maier dl. J Med Chem. 2005 Sep 22;48(19):5980-8. doi: 10.1021/jm050166g. J Med Chem. 2005. PMID: 16162001 Free PMC article.

4

2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity.

Brown DG, Maier DL, Sylvester MA, Hoerter TN, Menhaji-Klotz E, Lasota CC, Hirata LT, Wilkins DE, Scott CW, Trivedi S, Chen T, McCarthy DJ, Maciag CM, Sutton EJ, Cumberledge J, Mathisen D, Roberts J, Gupta A, Liu F, Elmore CS, Alhambra C, Krumrine JR, Wang X, Ciaccio PJ, Wood MW, Campbell JB, Johansson MJ, Xia J, Wen X, Jiang J, Wang X, Peng Z, Hu T, Wang J. Brown DG, et al. Among authors: maier dl. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3399-403. doi: 10.1016/j.bmcl.2011.03.117. Epub 2011 Apr 8. Bioorg Med Chem Lett. 2011. PMID: 21524576

5

Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activity.

Brown DG, Bernstein PR, Wu Y, Urbanek RA, Becker CW, Throner SR, Dembofsky BT, Steelman GB, Lazor LA, Scott CW, Wood MW, Wesolowski SS, Nugiel DA, Koch S, Yu J, Pivonka DE, Li S, Thompson C, Zacco A, Elmore CS, Schroeder P, Liu J, Hurley CA, Ward S, Hunt HJ, Williams K, McLaughlin J, Hoesch V, Sydserff S, Maier D, Aharony D. Brown DG, et al. ACS Med Chem Lett. 2012 Nov 12;4(1):46-51. doi: 10.1021/ml300262e. eCollection 2013 Jan 10. ACS Med Chem Lett. 2012. PMID: 24900562 Free PMC article.

6

[N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.

Maier DL, Sobotka-Briner C, Ding M, Powell ME, Jiang Q, Hill G, Heys JR, Elmore CS, Pierson ME, Mrzljak L. Maier DL, et al. J Pharmacol Exp Ther. 2009 Jul;330(1):342-51. doi: 10.1124/jpet.109.150722. Epub 2009 Apr 28. J Pharmacol Exp Ther. 2009. PMID: 19401496

7

Pre-clinical validation of a novel alpha-7 nicotinic receptor radiotracer, [(3)H]AZ11637326: target localization, biodistribution and ligand occupancy in the rat brain.

Maier DL, Hill G, Ding M, Tuke D, Einstein E, Gurley D, Gordon JC, Bock MJ, Smith JS, Bialecki R, Eisman M, Elmore CS, Werkheiser JL. Maier DL, et al. Neuropharmacology. 2011 Jul-Aug;61(1-2):161-71. doi: 10.1016/j.neuropharm.2011.03.024. Epub 2011 Apr 7. Neuropharmacology. 2011. PMID: 21497612

8

In vitro binding of a radio-labeled positive allosteric modulator for metabotropic glutamate receptor subtype 5.

Zysk JR, Spear N, Fieles W, Stein MM, Sygowski LS, King MM, Hoesch V, Hastings R, Brockel B, Do M, Ström P, Gadient R, Chhajlani V, Elmore CS, Maier DL. Zysk JR, et al. Among authors: maier dl. Synapse. 2013 Mar;67(3):135-44. doi: 10.1002/syn.21625. Epub 2012 Dec 6. Synapse. 2013. PMID: 23150216

9

D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]-MNPA, [3H]-(+)-PHNO, and [3H]-raclopride.

Peng T, Zysk J, Dorff P, Elmore CS, Ström P, Malmquist J, Ding M, Tuke D, Werkheiser J, Widzowski D, Mrzljak L, Maier D. Peng T, et al. Synapse. 2010 Aug;64(8):624-33. doi: 10.1002/syn.20771. Synapse. 2010. PMID: 20340171

10

[³H]Chiba-1001(methyl-SSR180711) has low in vitro binding affinity and poor in vivo selectivity to nicotinic alpha-7 receptor in rodent brain.

Ding M, Ghanekar S, Elmore CS, Zysk JR, Werkheiser JL, Lee CM, Liu J, Chhajlani V, Maier DL. Ding M, et al. Among authors: maier dl. Synapse. 2012 Apr;66(4):315-22. doi: 10.1002/syn.21513. Epub 2011 Dec 29. Synapse. 2012. PMID: 22108786

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