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Aging and survival: the genetics of life span extension by dietary restriction.
Mair W, Dillin A. Mair W, et al. Annu Rev Biochem. 2008;77:727-54. doi: 10.1146/annurev.biochem.77.061206.171059. Annu Rev Biochem. 2008. PMID: 18373439 Review.
Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.
Weir HJ, Yao P, Huynh FK, Escoubas CC, Goncalves RL, Burkewitz K, Laboy R, Hirschey MD, Mair WB. Weir HJ, et al. Cell Metab. 2017 Dec 5;26(6):884-896.e5. doi: 10.1016/j.cmet.2017.09.024. Epub 2017 Oct 26. Cell Metab. 2017. PMID: 29107506 Free PMC article.
A Systems Approach to Reverse Engineer Lifespan Extension by Dietary Restriction.
Hou L, Wang D, Chen D, Liu Y, Zhang Y, Cheng H, Xu C, Sun N, McDermott J, Mair WB, Han JD. Hou L, et al. Cell Metab. 2016 Mar 8;23(3):529-40. doi: 10.1016/j.cmet.2016.02.002. Cell Metab. 2016. PMID: 26959186 Free PMC article.
Endogenous hydrogen sulfide production is essential for dietary restriction benefits.
Hine C, Harputlugil E, Zhang Y, Ruckenstuhl C, Lee BC, Brace L, Longchamp A, TreviƱo-Villarreal JH, Mejia P, Ozaki CK, Wang R, Gladyshev VN, Madeo F, Mair WB, Mitchell JR. Hine C, et al. Cell. 2015 Jan 15;160(1-2):132-44. doi: 10.1016/j.cell.2014.11.048. Epub 2014 Dec 23. Cell. 2015. PMID: 25542313 Free PMC article.
Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes.
Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer MW. Capelson M, et al. Among authors: mair w. Cell. 2010 Feb 5;140(3):372-83. doi: 10.1016/j.cell.2009.12.054. Cell. 2010. PMID: 20144761 Free PMC article.
Reinforcing reinforcement.
Mair W. Mair W. PLoS Biol. 2010 Mar 23;8(3):e1000340. doi: 10.1371/journal.pbio.1000340. PLoS Biol. 2010. PMID: 20351768 Free PMC article. No abstract available.
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ. Egan DF, et al. Among authors: mair w. Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23. Science. 2011. PMID: 21205641 Free PMC article.
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. Mair W, et al. Nature. 2011 Feb 17;470(7334):404-8. doi: 10.1038/nature09706. Nature. 2011. PMID: 21331044 Free PMC article.
Dietary restriction enhances germline stem cell maintenance.
Mair W, McLeod CJ, Wang L, Jones DL. Mair W, et al. Aging Cell. 2010 Oct;9(5):916-8. doi: 10.1111/j.1474-9726.2010.00602.x. Aging Cell. 2010. PMID: 20569233 Free PMC article.
Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans.
Mair W, Panowski SH, Shaw RJ, Dillin A. Mair W, et al. PLoS One. 2009;4(2):e4535. doi: 10.1371/journal.pone.0004535. Epub 2009 Feb 20. PLoS One. 2009. PMID: 19229346 Free PMC article.
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