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Regulation and spatial organization of PCNA in Trypanosoma brucei.
Kaufmann D, Gassen A, Maiser A, Leonhardt H, Janzen CJ. Kaufmann D, et al. Among authors: maiser a. Biochem Biophys Res Commun. 2012 Mar 23;419(4):698-702. doi: 10.1016/j.bbrc.2012.02.082. Epub 2012 Feb 21. Biochem Biophys Res Commun. 2012. PMID: 22387477
As in most eukaryotic cells, replication is regulated by a conserved group of proteins in the early-diverged parasite Trypanosoma brucei. ...We characterized the proliferating cell nuclear antigen in T. brucei (TbPCNA) to establish a spatial and temporal marker for …
As in most eukaryotic cells, replication is regulated by a conserved group of proteins in the early-diverged parasite Trypanosoma bru …
4D Visualization of replication foci in mammalian cells corresponding to individual replicons.
Chagin VO, Casas-Delucchi CS, Reinhart M, Schermelleh L, Markaki Y, Maiser A, Bolius JJ, Bensimon A, Fillies M, Domaing P, Rozanov YM, Leonhardt H, Cardoso MC. Chagin VO, et al. Among authors: maiser a. Nat Commun. 2016 Apr 7;7:11231. doi: 10.1038/ncomms11231. Nat Commun. 2016. PMID: 27052570 Free PMC article.
Identification of the elementary structural units of the DNA damage response.
Natale F, Rapp A, Yu W, Maiser A, Harz H, Scholl A, Grulich S, Anton T, Hörl D, Chen W, Durante M, Taucher-Scholz G, Leonhardt H, Cardoso MC. Natale F, et al. Among authors: maiser a. Nat Commun. 2017 Jun 12;8:15760. doi: 10.1038/ncomms15760. Nat Commun. 2017. PMID: 28604675 Free PMC article.
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V. Rehage N, et al. Among authors: maiser a. Nat Commun. 2018 Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1. Nat Commun. 2018. PMID: 29352114 Free PMC article.
Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y.
Wiedemann SM, Mildner SN, Bönisch C, Israel L, Maiser A, Matheisl S, Straub T, Merkl R, Leonhardt H, Kremmer E, Schermelleh L, Hake SB. Wiedemann SM, et al. Among authors: maiser a. J Cell Biol. 2010 Sep 6;190(5):777-91. doi: 10.1083/jcb.201002043. J Cell Biol. 2010. PMID: 20819935 Free PMC article.
Transgenic H3.X and H3.Y proteins are stably incorporated into chromatin in a similar fashion to the known H3 variants. Importantly, we demonstrate biochemically and by mass spectrometry that endogenous H3.Y protein exists in vivo, and that stress stimuli, such as starvati …
Transgenic H3.X and H3.Y proteins are stably incorporated into chromatin in a similar fashion to the known H3 variants. Importantly, …
Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin.
Hahn M, Dambacher S, Dulev S, Kuznetsova AY, Eck S, Wörz S, Sadic D, Schulte M, Mallm JP, Maiser A, Debs P, von Melchner H, Leonhardt H, Schermelleh L, Rohr K, Rippe K, Storchova Z, Schotta G. Hahn M, et al. Among authors: maiser a. Genes Dev. 2013 Apr 15;27(8):859-72. doi: 10.1101/gad.210377.112. Epub 2013 Apr 18. Genes Dev. 2013. PMID: 23599346 Free PMC article.
Here we define the histone methyltransferase Suv4-20h2 as a major structural constituent of heterochromatin that mediates chromatin compaction and cohesin recruitment. ...
Here we define the histone methyltransferase Suv4-20h2 as a major structural constituent of heterochromatin that mediates chromatin c …
Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters.
Cremer M, Schmid VJ, Kraus F, Markaki Y, Hellmann I, Maiser A, Leonhardt H, John S, Stamatoyannopoulos J, Cremer T. Cremer M, et al. Among authors: maiser a. Epigenetics Chromatin. 2017 Aug 7;10(1):39. doi: 10.1186/s13072-017-0146-0. Epigenetics Chromatin. 2017. PMID: 28784182 Free PMC article.
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Andreeva L, et al. Among authors: maiser a. Nature. 2017 Sep 21;549(7672):394-398. doi: 10.1038/nature23890. Epub 2017 Sep 13. Nature. 2017. PMID: 28902841
Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.
Essig K, Hu D, Guimaraes JC, Alterauge D, Edelmann S, Raj T, Kranich J, Behrens G, Heiseke A, Floess S, Klein J, Maiser A, Marschall S, Hrabĕ de Angelis M, Leonhardt H, Calkhoven CF, Noessner E, Brocker T, Huehn J, Krug AB, Zavolan M, Baumjohann D, Heissmeyer V. Essig K, et al. Among authors: maiser a. Immunity. 2017 Dec 19;47(6):1067-1082.e12. doi: 10.1016/j.immuni.2017.11.008. Epub 2017 Dec 12. Immunity. 2017. PMID: 29246441 Free article.
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