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Prefoldin prevents aggregation of α-synuclein.
Takano M, Tashiro E, Kitamura A, Maita H, Iguchi-Ariga SM, Kinjo M, Ariga H. Takano M, et al. Among authors: maita h. Brain Res. 2014 Jan 13;1542:186-94. Brain Res. 2014. PMID: 24511594
Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation.
Abe A, Takahashi-Niki K, Takekoshi Y, Shimizu T, Kitaura H, Maita H, Iguchi-Ariga SM, Ariga H. Abe A, et al. Among authors: maita h. J Biol Chem. 2013 Sep 27;288(39):27764-76. doi: 10.1074/jbc.M113.476358. Epub 2013 Aug 14. J Biol Chem. 2013. PMID: 23946485 Free PMC article.
Neuroprotective function of DJ-1 in Parkinson's disease.
Ariga H, Takahashi-Niki K, Kato I, Maita H, Niki T, Iguchi-Ariga SM. Ariga H, et al. Among authors: maita h. Oxid Med Cell Longev. 2013;2013:683920. doi: 10.1155/2013/683920. Epub 2013 May 16. Oxid Med Cell Longev. 2013. PMID: 23766857 Free PMC article. Review.
Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats.
Kitamura Y, Watanabe S, Taguchi M, Takagi K, Kawata T, Takahashi-Niki K, Yasui H, Maita H, Iguchi-Ariga SM, Ariga H. Kitamura Y, et al. Among authors: maita h. Mol Neurodegener. 2011 Jul 8;6(1):48. doi: 10.1186/1750-1326-6-48. Mol Neurodegener. 2011. PMID: 21740546 Free PMC article.
DJ-1 binds to mitochondrial complex I and maintains its activity.
Hayashi T, Ishimori C, Takahashi-Niki K, Taira T, Kim YC, Maita H, Maita C, Ariga H, Iguchi-Ariga SM. Hayashi T, et al. Among authors: maita h, maita c. Biochem Biophys Res Commun. 2009 Dec 18;390(3):667-72. doi: 10.1016/j.bbrc.2009.10.025. Epub 2009 Oct 12. Biochem Biophys Res Commun. 2009. PMID: 19822128
DJ-1-Mediated protective effect of protocatechuic aldehyde against oxidative stress in SH-SY5Y cells.
Gao JW, Yamane T, Maita H, Ishikawa S, Iguchi-Ariga SM, Pu XP, Ariga H. Gao JW, et al. Among authors: maita h. J Pharmacol Sci. 2011;115(1):36-44. doi: 10.1254/jphs.10271fp. Epub 2010 Dec 11. J Pharmacol Sci. 2011. PMID: 21160133
Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein.
Takahashi-Niki K, Kato-Ose I, Murata H, Maita H, Iguchi-Ariga SM, Ariga H. Takahashi-Niki K, et al. Among authors: maita h. J Biol Chem. 2015 Jul 17;290(29):17838-47. doi: 10.1074/jbc.M115.666271. Epub 2015 Jun 5. J Biol Chem. 2015. PMID: 26048984 Free PMC article.
Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits.
Miyazawa M, Tashiro E, Kitaura H, Maita H, Suto H, Iguchi-Ariga SM, Ariga H. Miyazawa M, et al. Among authors: maita h. J Biol Chem. 2011 Jun 3;286(22):19191-203. doi: 10.1074/jbc.M110.216259. Epub 2011 Apr 8. J Biol Chem. 2011. PMID: 21478150 Free PMC article.
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