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Multiplex qPCR assay for ultra sensitive detection of JCV DNA with simultaneous identification of genotypes that discriminates non-virulent from virulent variants.
Ryschkewitsch CF, Jensen PN, Major EO. Ryschkewitsch CF, et al. Among authors: major eo. J Clin Virol. 2013 Jul;57(3):243-8. doi: 10.1016/j.jcv.2013.03.009. Epub 2013 Apr 23. J Clin Virol. 2013. PMID: 23619054 Free PMC article.
JC virus quasispecies analysis reveals a complex viral population underlying progressive multifocal leukoencephalopathy and supports viral dissemination via the hematogenous route.
Van Loy T, Thys K, Ryschkewitsch C, Lagatie O, Monaco MC, Major EO, Tritsmans L, Stuyver LJ. Van Loy T, et al. Among authors: major eo. J Virol. 2015 Jan 15;89(2):1340-7. doi: 10.1128/JVI.02565-14. Epub 2014 Nov 12. J Virol. 2015. PMID: 25392214 Free PMC article.
False negative PCR despite high levels of JC virus DNA in spinal fluid: Implications for diagnostic testing.
Landry ML, Eid T, Bannykh S, Major E. Landry ML, et al. J Clin Virol. 2008 Oct;43(2):247-9. doi: 10.1016/j.jcv.2008.07.003. Epub 2008 Aug 12. J Clin Virol. 2008. PMID: 18701345 Free PMC article.
Management of infections by the human polyomavirus JC: past, present and future.
Hou J, Major E. Hou J, et al. Expert Rev Anti Infect Ther. 2005 Aug;3(4):629-40. doi: 10.1586/14787210.3.4.629. Expert Rev Anti Infect Ther. 2005. PMID: 16107201 Review.
Characterization of JC human polyomavirus infection in a Portuguese population.
Matos A, Duque V, Beato S, da Silva JP, Major E, Meli├žo-Silvestre A. Matos A, et al. J Med Virol. 2010 Mar;82(3):494-504. doi: 10.1002/jmv.21710. J Med Virol. 2010. PMID: 20087944
JC virus in CD34+ and CD19+ cells in patients with multiple sclerosis treated with natalizumab.
Frohman EM, Monaco MC, Remington G, Ryschkewitsch C, Jensen PN, Johnson K, Perkins M, Liebner J, Greenberg B, Monson N, Frohman TC, Douek D, Major EO. Frohman EM, et al. Among authors: major eo. JAMA Neurol. 2014 May;71(5):596-602. doi: 10.1001/jamaneurol.2014.63. JAMA Neurol. 2014. PMID: 24664166
Changes in JC virus-specific T cell responses during natalizumab treatment and in natalizumab-associated progressive multifocal leukoencephalopathy.
Perkins MR, Ryschkewitsch C, Liebner JC, Monaco MC, Himelfarb D, Ireland S, Roque A, Edward HL, Jensen PN, Remington G, Abraham T, Abraham J, Greenberg B, Kaufman C, LaGanke C, Monson NL, Xu X, Frohman E, Major EO, Douek DC. Perkins MR, et al. Among authors: major eo. PLoS Pathog. 2012;8(11):e1003014. doi: 10.1371/journal.ppat.1003014. Epub 2012 Nov 8. PLoS Pathog. 2012. PMID: 23144619 Free PMC article. Clinical Trial.
JC virus persistence following progressive multifocal leukoencephalopathy in multiple sclerosis patients treated with natalizumab.
Ryschkewitsch CF, Jensen PN, Monaco MC, Major EO. Ryschkewitsch CF, et al. Among authors: major eo. Ann Neurol. 2010 Sep;68(3):384-91. doi: 10.1002/ana.22137. Ann Neurol. 2010. PMID: 20818792 Free PMC article.
Pathogenesis of progressive multifocal leukoencephalopathy and risks associated with treatments for multiple sclerosis: a decade of lessons learned.
Major EO, Yousry TA, Clifford DB. Major EO, et al. Lancet Neurol. 2018 May;17(5):467-480. doi: 10.1016/S1474-4422(18)30040-1. Lancet Neurol. 2018. PMID: 29656742 Review.
JC virus granule cell neuronopathy in the setting of chronic lymphopenia treated with recombinant interleukin-7.
Soleimani-Meigooni DN, Schwetye KE, Angeles MR, Ryschkewitsch CF, Major EO, Dang X, Koralnik IJ, Schmidt RE, Clifford DB, Kuhlmann FM, Bucelli RC. Soleimani-Meigooni DN, et al. Among authors: major eo. J Neurovirol. 2017 Feb;23(1):141-146. doi: 10.1007/s13365-016-0465-0. Epub 2016 Jul 15. J Neurovirol. 2017. PMID: 27421731 Free PMC article.
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