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The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo.
Funnell AP, Norton LJ, Mak KS, Burdach J, Artuz CM, Twine NA, Wilkins MR, Power CA, Hung TT, Perdomo J, Koh P, Bell-Anderson KS, Orkin SH, Fraser ST, Perkins AC, Pearson RC, Crossley M. Funnell AP, et al. Among authors: mak ks. Mol Cell Biol. 2012 Aug;32(16):3281-92. doi: 10.1128/MCB.00173-12. Epub 2012 Jun 18. Mol Cell Biol. 2012. PMID: 22711990 Free PMC article.
Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).
Bell-Anderson KS, Funnell AP, Williams H, Mat Jusoh H, Scully T, Lim WF, Burdach JG, Mak KS, Knights AJ, Hoy AJ, Nicholas HR, Sainsbury A, Turner N, Pearson RC, Crossley M. Bell-Anderson KS, et al. Among authors: mak ks. Diabetes. 2013 Aug;62(8):2728-37. doi: 10.2337/db12-1745. Epub 2013 Apr 30. Diabetes. 2013. PMID: 23633521 Free PMC article.
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing.
Funnell AP, Mak KS, Twine NA, Pelka GJ, Norton LJ, Radziewic T, Power M, Wilkins MR, Bell-Anderson KS, Fraser ST, Perkins AC, Tam PP, Pearson RC, Crossley M. Funnell AP, et al. Among authors: mak ks. Mol Cell Biol. 2013 Aug;33(15):2976-87. doi: 10.1128/MCB.00074-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716600 Free PMC article.
PU.1 and Haematopoietic Cell Fate: Dosage Matters.
Mak KS, Funnell AP, Pearson RC, Crossley M. Mak KS, et al. Int J Cell Biol. 2011;2011:808524. doi: 10.1155/2011/808524. Epub 2011 Aug 10. Int J Cell Biol. 2011. PMID: 21845190 Free PMC article.
Impaired B cell development in the absence of Krüppel-like factor 3.
Vu TT, Gatto D, Turner V, Funnell AP, Mak KS, Norton LJ, Kaplan W, Cowley MJ, Agenès F, Kirberg J, Brink R, Pearson RC, Crossley M. Vu TT, et al. Among authors: mak ks. J Immunol. 2011 Nov 15;187(10):5032-42. doi: 10.4049/jimmunol.1101450. Epub 2011 Oct 14. J Immunol. 2011. PMID: 22003205
Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity.
Dewi V, Kwok A, Lee S, Lee MM, Tan YM, Nicholas HR, Isono K, Wienert B, Mak KS, Knights AJ, Quinlan KG, Cordwell SJ, Funnell AP, Pearson RC, Crossley M. Dewi V, et al. Among authors: mak ks. J Biol Chem. 2015 Mar 27;290(13):8591-605. doi: 10.1074/jbc.M115.638338. Epub 2015 Feb 6. J Biol Chem. 2015. PMID: 25659434 Free PMC article.
70 results