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Binase cleaves cellular noncoding RNAs and affects coding mRNAs.
Mitkevich VA, Tchurikov NA, Zelenikhin PV, Petrushanko IY, Makarov AA, Ilinskaya ON. Mitkevich VA, et al. Among authors: makarov aa. FEBS J. 2010 Jan;277(1):186-96. doi: 10.1111/j.1742-4658.2009.07471.x. Epub 2009 Nov 26. FEBS J. 2010. PMID: 19968715
[Cytotoxicity mechanism of the RNase Sa cationic mutants involves inhibition of potassium current through Ca2+-activated channels].
Mitkevich VA, Pace CN, Koschinski A, Makarov AA, Ilinskaya ON. Mitkevich VA, et al. Among authors: makarov aa. Mol Biol (Mosk). 2015 Nov-Dec;49(6):1041-7. doi: 10.7868/S0026898415060191. Mol Biol (Mosk). 2015. PMID: 26710788 Russian.
Comparative study of binase and barnase: experience in chimeric ribonucleases.
Schulga A, Kurbanov F, Kirpichnikov M, Protasevich I, Lobachov V, Ranjbar B, Chekhov V, Polyakov K, Engelborghs Y, Makarov A. Schulga A, et al. Among authors: makarov a. Protein Eng. 1998 Sep;11(9):775-82. doi: 10.1093/protein/11.9.775. Protein Eng. 1998. PMID: 9796826
Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis.
Makarov AA, Yakovlev GI, Mitkevich VA, Higgin JJ, Raines RT. Makarov AA, et al. Biochem Biophys Res Commun. 2004 Jun 18;319(1):152-6. doi: 10.1016/j.bbrc.2004.04.182. Biochem Biophys Res Commun. 2004. PMID: 15158454
Cytotoxicity of RNases is increased by cationization and counteracted by K(Ca) channels.
Ilinskaya ON, Koschinski A, Mitkevich VA, Repp H, Dreyer F, Pace CN, Makarov AA. Ilinskaya ON, et al. Among authors: makarov aa. Biochem Biophys Res Commun. 2004 Feb 6;314(2):550-4. doi: 10.1016/j.bbrc.2003.12.110. Biochem Biophys Res Commun. 2004. PMID: 14733942
Cytotoxic ribonucleases: molecular weapons and their targets.
Makarov AA, Ilinskaya ON. Makarov AA, et al. FEBS Lett. 2003 Apr 10;540(1-3):15-20. doi: 10.1016/s0014-5793(03)00225-4. FEBS Lett. 2003. PMID: 12681476 Review.
Cytotoxicity of RNase Sa to the acute myeloid leukemia Kasumi-1 cells depends on the net charge.
Mitkevich VA, Burnysheva KM, Ilinskaya ON, Pace CN, Makarov AA. Mitkevich VA, et al. Among authors: makarov aa. Oncoscience. 2014 Nov 10;1(11):738-44. doi: 10.18632/oncoscience.97. eCollection 2014. Oncoscience. 2014. PMID: 25594000 Free PMC article.
Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins.
Mitkevich VA, Burnysheva KM, Petrushanko IY, Adzhubei AA, Schulga AA, Chumakov PM, Makarov AA. Mitkevich VA, et al. Among authors: makarov aa. Oncotarget. 2017 Aug 10;8(42):72666-72675. doi: 10.18632/oncotarget.20199. eCollection 2017 Sep 22. Oncotarget. 2017. PMID: 29069817 Free PMC article.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Mironova NL, Petrushanko IY, Patutina OA, Sen'kova AV, Simonenko OV, Mitkevich VA, Markov OV, Zenkova MA, Makarov AA. Mironova NL, et al. Among authors: makarov aa. Cell Cycle. 2013 Jul 1;12(13):2120-31. doi: 10.4161/cc.25164. Epub 2013 Jun 10. Cell Cycle. 2013. PMID: 23759588 Free PMC article.
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