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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, Furuta H, Hirota Y, Mori H, Jonsson A, Sato Y, Yamagata K, Hinokio Y, Wang HY, Tanahashi T, Nakamura N, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Takeda J, Maeda E, Shin HD, Cho YM, Park KS, Lee HK, Ng MC, Ma RC, So WY, Chan JC, Lyssenko V, Tuomi T, Nilsson P, Groop L, Kamatani N, Sekine A, Nakamura Y, Yamamoto K, Yoshida T, Tokunaga K, Itakura M, Makino H, Nanjo K, Kadowaki T, Kasuga M. Yasuda K, et al. Among authors: makino h. Nat Genet. 2008 Sep;40(9):1092-7. doi: 10.1038/ng.207. Nat Genet. 2008. PMID: 18711367
Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.
Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: makino h. Diabetes. 2003 Feb;52(2):562-7. doi: 10.2337/diabetes.52.2.562. Diabetes. 2003. PMID: 12540636
Systematic search for single nucleotide polymorphisms in the 5' flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes.
Osawa H, Niiya T, Onuma H, Murakami A, Ochi M, Nishimiya T, Ogura T, Kato K, Shimizu I, Fujii Y, Ohashi J, Yamada K, Liang SJ, Manganiello VC, Fujita-Yamaguchi Y, Makino H. Osawa H, et al. Among authors: makino h. Mol Genet Metab. 2003 May;79(1):43-51. doi: 10.1016/s1096-7192(03)00035-0. Mol Genet Metab. 2003. PMID: 12765845
The absence of evidence for major effects of the frequent SNP +299G>A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes.
Ochi M, Osawa H, Onuma H, Murakami A, Nishimiya T, Shimada F, Kato K, Shimizu I, Shishino K, Murase M, Fujii Y, Ohashi J, Makino H. Ochi M, et al. Among authors: makino h. Diabetes Res Clin Pract. 2003 Sep;61(3):191-8. doi: 10.1016/s0168-8227(03)00119-0. Diabetes Res Clin Pract. 2003. PMID: 12965109
The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.
Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: makino h. Am J Hum Genet. 2004 Oct;75(4):678-86. doi: 10.1086/424761. Epub 2004 Aug 26. Am J Hum Genet. 2004. PMID: 15338456 Free PMC article.
Differences in the contribution of HLA-DR and -DQ haplotypes to susceptibility to adult- and childhood-onset type 1 diabetes in Japanese patients.
Murao S, Makino H, Kaino Y, Konoue E, Ohashi J, Kida K, Fujii Y, Shimizu I, Kawasaki E, Fujiyama M, Kondo S, Tanaka K, Tarumi Y, Seto I, Kato K, Ohno K, Kusunoki Y, Ebisui O, Takada Y, Tanabe K, Takemoto K, Onuma H, Nishimiya T, Osawa H. Murao S, et al. Among authors: makino h. Diabetes. 2004 Oct;53(10):2684-90. doi: 10.2337/diabetes.53.10.2684. Diabetes. 2004. PMID: 15448101
1,929 results