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Mechanisms of thyrotropin receptor-mediated phenotype variability deciphered by gene mutations and M453T-knockin model.
Makkonen K, Jännäri M, Crisóstomo L, Kuusi M, Patyra K, Melnyk V, Linnossuo V, Ojala J, Ravi R, Löf C, Mäkelä JA, Miettinen P, Laakso S, Ojaniemi M, Jääskeläinen J, Laakso M, Bossowski F, Sawicka B, Stożek K, Bossowski A, Kleinau G, Scheerer P, FinnGen F, Reeve MP, Kero J. Makkonen K, et al. JCI Insight. 2024 Jan 9;9(4):e167092. doi: 10.1172/jci.insight.167092. JCI Insight. 2024. PMID: 38194289 Free article.
Critical evaluation of deep neural networks for wrist fracture detection.
Raisuddin AM, Vaattovaara E, Nevalainen M, Nikki M, Järvenpää E, Makkonen K, Pinola P, Palsio T, Niemensivu A, Tervonen O, Tiulpin A. Raisuddin AM, et al. Among authors: makkonen k. Sci Rep. 2021 Mar 16;11(1):6006. doi: 10.1038/s41598-021-85570-2. Sci Rep. 2021. PMID: 33727668 Free PMC article.
Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.
Jokela TA, Kärnä R, Makkonen KM, Laitinen JT, Tammi RH, Tammi MI. Jokela TA, et al. Among authors: makkonen km. J Biol Chem. 2014 Jun 27;289(26):18569-81. doi: 10.1074/jbc.M114.551804. Epub 2014 May 20. J Biol Chem. 2014. PMID: 24847057 Free PMC article.
43 results