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In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance.
da Silva Ferreira ME, Capellaro JL, dos Reis Marques E, Malavazi I, Perlin D, Park S, Anderson JB, Colombo AL, Arthington-Skaggs BA, Goldman MH, Goldman GH. da Silva Ferreira ME, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4405-13. doi: 10.1128/AAC.48.11.4405-4413.2004. Antimicrob Agents Chemother. 2004. PMID: 15504870 Free PMC article.
The Aspergillus nidulans sldI(RAD50) gene interacts with bimE(APC1), a homologue of an anaphase-promoting complex subunit.
Malavazi I, Lima JF, von Zeska Kress Fagundes MR, Efimov VP, de Souza Goldman MH, Goldman GH. Malavazi I, et al. Mol Microbiol. 2005 Jul;57(1):222-37. doi: 10.1111/j.1365-2958.2005.04671.x. Mol Microbiol. 2005. PMID: 15948962
Our results suggest a possible novel feature of the Mre11 complex in A. nidulans, i.e. a relationship with bimE (APC1)....
Our results suggest a possible novel feature of the Mre11 complex in A. nidulans, i.e. a relationship with bimE (APC1)....
Transcriptome analysis of Aspergillus fumigatus exposed to voriconazole.
da Silva Ferreira ME, Malavazi I, Savoldi M, Brakhage AA, Goldman MH, Kim HS, Nierman WC, Goldman GH. da Silva Ferreira ME, et al. Curr Genet. 2006 Jul;50(1):32-44. doi: 10.1007/s00294-006-0073-2. Epub 2006 Apr 19. Curr Genet. 2006. PMID: 16622700
In our study, we have observed: (i) a decreased mRNA expression of various ergosterol biosynthesis genes; (ii) increased mRNA levels of genes involved in a variety of cell functions, such as transporters, transcription factors, proteins involved in cell metabolism, and hyp …
In our study, we have observed: (i) a decreased mRNA expression of various ergosterol biosynthesis genes; (ii) increased mRNA levels …
Transcriptome analysis of Aspergillus nidulans exposed to camptothecin-induced DNA damage.
Malavazi I, Savoldi M, Di Mauro SM, Menck CF, Harris SD, Goldman MH, Goldman GH. Malavazi I, et al. Eukaryot Cell. 2006 Oct;5(10):1688-704. doi: 10.1128/EC.00167-06. Eukaryot Cell. 2006. PMID: 17030995 Free PMC article.
Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.
Malavazi I, Savoldi M, da Silva Ferreira ME, Soriani FM, Bonato PS, de Souza Goldman MH, Goldman GH. Malavazi I, et al. Mol Microbiol. 2007 Oct;66(1):74-99. doi: 10.1111/j.1365-2958.2007.05885.x. Mol Microbiol. 2007. PMID: 17880424
Functional characterization of the putative Aspergillus nidulans DNA damage binding protein homologue DdbA.
Lima JF, Malavazi I, da Silva Ferreira ME, Savoldi M, Mota AO Jr, Capellaro JL, de Souza Goldman MH, Goldman GH. Lima JF, et al. Mol Genet Genomics. 2008 Mar;279(3):239-53. doi: 10.1007/s00438-007-0307-0. Epub 2007 Nov 30. Mol Genet Genomics. 2008. PMID: 18060432
Genetic interactions of the Aspergillus nidulans atmAATM homolog with different components of the DNA damage response pathway.
Malavazi I, Lima JF, de Castro PA, Savoldi M, de Souza Goldman MH, Goldman GH. Malavazi I, et al. Genetics. 2008 Feb;178(2):675-91. doi: 10.1534/genetics.107.080879. Epub 2008 Feb 1. Genetics. 2008. PMID: 18245360 Free PMC article.
Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.
Soriani FM, Malavazi I, da Silva Ferreira ME, Savoldi M, Von Zeska Kress MR, de Souza Goldman MH, Loss O, Bignell E, Goldman GH. Soriani FM, et al. Mol Microbiol. 2008 Mar;67(6):1274-91. doi: 10.1111/j.1365-2958.2008.06122.x. Epub 2008 Feb 20. Mol Microbiol. 2008. PMID: 18298443
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