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Advances in the use of nanoscale bilayers to study membrane protein structure and function.
Malhotra K, Alder NN. Malhotra K, et al. Biotechnol Genet Eng Rev. 2014 Oct;30(1-2):79-93. doi: 10.1080/02648725.2014.921502. Biotechnol Genet Eng Rev. 2014. PMID: 25023464 Review.
Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50.
Malhotra K, Modak A, Nangia S, Daman TH, Gunsel U, Robinson VL, Mokranjac D, May ER, Alder NN. Malhotra K, et al. Sci Adv. 2017 Sep 1;3(9):e1700532. doi: 10.1126/sciadv.1700532. eCollection 2017 Sep. Sci Adv. 2017. PMID: 28879236 Free PMC article.
Reconstitution of Mitochondrial Membrane Proteins into Nanodiscs by Cell-Free Expression.
Malhotra K, Alder NN. Malhotra K, et al. Methods Mol Biol. 2017;1567:155-178. doi: 10.1007/978-1-4939-6824-4_10. Methods Mol Biol. 2017. PMID: 28276018 Free PMC article.
A detergent-free strategy for the reconstitution of active enzyme complexes from native biological membranes into nanoscale discs.
Long AR, O'Brien CC, Malhotra K, Schwall CT, Albert AD, Watts A, Alder NN. Long AR, et al. Among authors: malhotra k. BMC Biotechnol. 2013 May 11;13:41. doi: 10.1186/1472-6750-13-41. BMC Biotechnol. 2013. PMID: 23663692 Free PMC article.
Structural changes in the mitochondrial Tim23 channel are coupled to the proton-motive force.
Malhotra K, Sathappa M, Landin JS, Johnson AE, Alder NN. Malhotra K, et al. Nat Struct Mol Biol. 2013 Aug;20(8):965-72. doi: 10.1038/nsmb.2613. Epub 2013 Jul 7. Nat Struct Mol Biol. 2013. PMID: 23832274
Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition.
Kumar A, Saigal K, Malhotra K, Sinha KM, Taneja B. Kumar A, et al. Among authors: malhotra k. J Biol Chem. 2011 Jun 3;286(22):19652-61. doi: 10.1074/jbc.M110.200428. Epub 2011 Apr 7. J Biol Chem. 2011. PMID: 21474448 Free PMC article.
Characterization of (6-4) photoproduct DNA photolyase.
Kim ST, Malhotra K, Smith CA, Taylor JS, Sancar A. Kim ST, et al. Among authors: malhotra k. J Biol Chem. 1994 Mar 18;269(11):8535-40. J Biol Chem. 1994. PMID: 8132580
Substitution of lysine 213 with arginine in penicillin-binding protein 5 of Escherichia coli abolishes D-alanine carboxypeptidase activity without affecting penicillin binding.
Malhotra KT, Nicholas RA. Malhotra KT, et al. J Biol Chem. 1992 Jun 5;267(16):11386-91. J Biol Chem. 1992. PMID: 1597468
Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23.
Liu L, Thaker TM, Freed DM, Frazier N, Malhotra K, Lemmon MA, Jura N. Liu L, et al. Among authors: malhotra k. Structure. 2018 Feb 6;26(2):270-281.e4. doi: 10.1016/j.str.2017.12.012. Epub 2018 Jan 18. Structure. 2018. PMID: 29358026 Free PMC article.
Purification and characterization of Drosophila melanogaster photolyase.
Kim ST, Malhotra K, Ryo H, Sancar A, Todo T. Kim ST, et al. Among authors: malhotra k. Mutat Res. 1996 Jun 12;363(2):97-104. doi: 10.1016/0921-8777(96)00003-1. Mutat Res. 1996. PMID: 8676930
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