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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1930 1
1946 1
1947 8
1948 6
1949 3
1950 4
1951 11
1952 7
1953 2
1954 5
1955 6
1956 2
1957 4
1958 3
1959 9
1960 7
1961 11
1962 17
1963 13
1964 13
1965 24
1966 9
1967 6
1968 10
1969 13
1970 7
1971 10
1972 5
1973 8
1974 2
1975 12
1976 8
1977 12
1978 8
1979 9
1980 12
1981 24
1982 41
1983 34
1984 49
1985 59
1986 45
1987 39
1988 46
1989 36
1990 43
1991 38
1992 50
1993 39
1994 50
1995 40
1996 47
1997 49
1998 46
1999 58
2000 77
2001 78
2002 99
2003 93
2004 79
2005 100
2006 110
2007 116
2008 121
2009 138
2010 148
2011 166
2012 198
2013 200
2014 207
2015 219
2016 255
2017 237
2018 264
2019 286
2020 285
2021 294
2022 322
2023 44
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4,667 results
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Page 1
Magnesium and malic acid supplement for fibromyalgia.
Ferreira I, Ortigoza Á, Moore P. Ferreira I, et al. Medwave. 2019 May 28;19(4):e7633. doi: 10.5867/medwave.2019.04.7632. Medwave. 2019. PMID: 31150373 English, Spanish.
RESULTS AND CONCLUSIONS: We identified seven systematic reviews which included 11 primary studies of which one was a randomized trial. Our conclusion is that the use of magnesium and malic acid in patients with fibromyalgia makes little or no difference on pain and …
RESULTS AND CONCLUSIONS: We identified seven systematic reviews which included 11 primary studies of which one was a randomized trial. Our c …
Recent advances in microbial production of L-malic acid.
Wu N, Zhang J, Chen Y, Xu Q, Song P, Li Y, Li K, Liu H. Wu N, et al. Appl Microbiol Biotechnol. 2022 Dec;106(24):7973-7992. doi: 10.1007/s00253-022-12260-y. Epub 2022 Nov 12. Appl Microbiol Biotechnol. 2022. PMID: 36370160 Review.
L-malic acid is currently mainly fabricated through a fumarate hydratase-based biocatalytic conversion route, wherein petroleum-derived fumaric acid serves as a substrate. ...First, we summarize the various pathways involved in L-malic acid bios …
L-malic acid is currently mainly fabricated through a fumarate hydratase-based biocatalytic conversion route, wherein petroleu …
L-malic acid production from xylose by engineered Saccharomyces cerevisiae.
Kang NK, Lee JW, Ort DR, Jin YS. Kang NK, et al. Biotechnol J. 2022 Mar;17(3):e2000431. doi: 10.1002/biot.202000431. Epub 2021 Aug 25. Biotechnol J. 2022. PMID: 34390209
L-malic acid is widely used in the food, chemical, and pharmaceutical industries. ...Additionally, both the ethanol and glycerol-producing pathways were blocked to enhance malic acid production. The resulting strain produced malic acid fr …
L-malic acid is widely used in the food, chemical, and pharmaceutical industries. ...Additionally, both the ethanol and glycer …
Enzyme-based amperometric biosensors for malic acid - A review.
Matthews CJ, Andrews ESV, Patrick WM. Matthews CJ, et al. Anal Chim Acta. 2021 Apr 29;1156:338218. doi: 10.1016/j.aca.2021.338218. Epub 2021 Jan 21. Anal Chim Acta. 2021. PMID: 33781460 Review.
Malic acid is a key flavour component of many fruits and vegetables. ...A particular focus of our review is the three types of malate oxidoreductase enzyme that have been used in malic acid biosensors. We describe their different properties and conclud …
Malic acid is a key flavour component of many fruits and vegetables. ...A particular focus of our review is the three types of …
Microbial biosynthesis and secretion of l-malic acid and its applications.
Chi Z, Wang ZP, Wang GY, Khan I, Chi ZM. Chi Z, et al. Crit Rev Biotechnol. 2016;36(1):99-107. doi: 10.3109/07388551.2014.924474. Epub 2014 Jul 15. Crit Rev Biotechnol. 2016. PMID: 25025277 Review.
l-Malic acid has many uses in food, beverage, pharmaceutical, chemical and medical industries. ...The pathways of l-malic acid biosynthesis in microorganisms are partially clear and three metabolic pathways including non-oxidative pathway, oxidative pa …
l-Malic acid has many uses in food, beverage, pharmaceutical, chemical and medical industries. ...The pathways of l-malic …
L-Malic Acid Protects Lacticaseibacillus paracasei L9 from Glycodeoxycholic Acid Stress via the Malolactic Enzyme Pathway.
Huan R, Zhai Z, An J, Ma X, Hao Y. Huan R, et al. J Agric Food Chem. 2022 Jul 27;70(29):9007-9016. doi: 10.1021/acs.jafc.2c02453. Epub 2022 Jul 14. J Agric Food Chem. 2022. PMID: 35833866
Bile tolerance specificity assays revealed that Lc. paracasei L9 was more sensitive to GDCA than to taurocholic acid, glycocholic acid, and taurodeoxycholic acid. Notably, l-malic acid significantly enhanced the GDCA tolerance of Lc. paracasei L …
Bile tolerance specificity assays revealed that Lc. paracasei L9 was more sensitive to GDCA than to taurocholic acid, glycocholic …
Techno economic analysis of malic acid production using crude glycerol derived from waste cooking oil.
Bharathiraja B, Jayamuthunagai J, Sreejith R, Iyyappan J, Praveenkumar R. Bharathiraja B, et al. Bioresour Technol. 2022 May;351:126956. doi: 10.1016/j.biortech.2022.126956. Epub 2022 Mar 7. Bioresour Technol. 2022. PMID: 35272039
The optimal condition for malic acid biosynthesis was studied by using response surface methodology. ...The cost involved for malic acid synthesis per unit volume was likely expected to be $0.43/kg of malic acid using reactive extraction …
The optimal condition for malic acid biosynthesis was studied by using response surface methodology. ...The cost involved for …
Optimization of L-malic acid production from acetate with Aspergillus oryzae DSM 1863 using a pH-coupled feeding strategy.
Kövilein A, Aschmann V, Zadravec L, Ochsenreither K. Kövilein A, et al. Microb Cell Fact. 2022 Nov 23;21(1):242. doi: 10.1186/s12934-022-01961-8. Microb Cell Fact. 2022. PMID: 36419102 Free PMC article.
BACKGROUND: Malic acid, a dicarboxylic acid mainly used in the food industry, is currently produced from fossil resources. ...In these experiments, malate and succinate, which is a major by-product during malic acid production, were added at con …
BACKGROUND: Malic acid, a dicarboxylic acid mainly used in the food industry, is currently produced from fossil resourc …
Expression of Escherichia coli malic enzyme gene in Zymomonas mobilis for production of malic acid.
Khandelwal R, Srivastava P, Bisaria VS. Khandelwal R, et al. J Biotechnol. 2022 Jun 10;351:23-29. doi: 10.1016/j.jbiotec.2022.04.007. Epub 2022 Apr 26. J Biotechnol. 2022. PMID: 35483474
Malic acid is one of the organic acids which is used in various industries including food and pharmaceuticals. ...In this study, malic acid synthesis by Zymomonas mobilis was studied by expressing Escherichia coli malic enzyme gene under Pchap, …
Malic acid is one of the organic acids which is used in various industries including food and pharmaceuticals. ...In this stud …
Malo-ethanolic fermentation in Saccharomyces and Schizosaccharomyces.
Volschenk H, van Vuuren HJ, Viljoen-Bloom M. Volschenk H, et al. Curr Genet. 2003 Sep;43(6):379-91. doi: 10.1007/s00294-003-0411-6. Epub 2003 Jun 12. Curr Genet. 2003. PMID: 12802505 Review.
The ability of a yeast strain to degrade extracellular malic acid is dependent on both the efficient transport of the dicarboxylic acid and the efficacy of the intracellular malic enzyme. The malic enzyme converts malic acid into p …
The ability of a yeast strain to degrade extracellular malic acid is dependent on both the efficient transport of the dicarbox …
4,667 results