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Electrophysiological characterization of granule cells in the dentate gyrus immediately after birth.
Pedroni A, Minh do D, Mallamaci A, Cherubini E. Pedroni A, et al. Front Cell Neurosci. 2014 Feb 14;8:44. doi: 10.3389/fncel.2014.00044. eCollection 2014. Front Cell Neurosci. 2014. PMID: 24592213 Free PMC article.
Neurogenesis reaches a peak at the end of the first postnatal week and it is completed at the end of the first postnatal month. This process continues at a reduced rate throughout life. Interestingly, immediately after birth, GCs exhibit a clear GABAergic phe …
Neurogenesis reaches a peak at the end of the first postnatal week and it is completed at the end of the first postnatal month. This …
DMRT5, DMRT3, and EMX2 Cooperatively Repress Gsx2 at the Pallium-Subpallium Boundary to Maintain Cortical Identity in Dorsal Telencephalic Progenitors.
Desmaris E, Keruzore M, Saulnier A, Ratié L, Assimacopoulos S, De Clercq S, Nan X, Roychoudhury K, Qin S, Kricha S, Chevalier C, Lingner T, Henningfeld KA, Zarkower D, Mallamaci A, Theil T, Campbell K, Pieler T, Li M, Grove EA, Bellefroid EJ. Desmaris E, et al. Among authors: mallamaci a. J Neurosci. 2018 Oct 17;38(42):9105-9121. doi: 10.1523/JNEUROSCI.0375-18.2018. Epub 2018 Aug 24. J Neurosci. 2018. PMID: 30143575 Free PMC article.
Reprogramming fibroblasts to neural-precursor-like cells by structured overexpression of pallial patterning genes.
Raciti M, Granzotto M, Duc MD, Fimiani C, Cellot G, Cherubini E, Mallamaci A. Raciti M, et al. Mol Cell Neurosci. 2013 Nov;57:42-53. doi: 10.1016/j.mcn.2013.10.004. Epub 2013 Oct 12. Mol Cell Neurosci. 2013. PMID: 24128663
Remarkably, a fraction of the reprogrammed population expressed other NSC markers and retained its new identity, even after switching off the reprogramming transgenes. When transferred into a pro-differentiative environment, Pax6/Foxg1-overexpressing cells activated …
Remarkably, a fraction of the reprogrammed population expressed other NSC markers and retained its new identity, even after switching …
Emx2 as a novel tool to suppress glioblastoma.
Falcone C, Daga A, Leanza G, Mallamaci A. Falcone C, et al. Among authors: mallamaci a. Oncotarget. 2016 Jul 5;7(27):41005-41016. doi: 10.18632/oncotarget.9322. Oncotarget. 2016. PMID: 27191499 Free PMC article.
The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.
Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Götz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ. Saulnier A, et al. Cereb Cortex. 2013 Nov;23(11):2552-67. doi: 10.1093/cercor/bhs234. Epub 2012 Aug 23. Cereb Cortex. 2013. PMID: 22923088 Free PMC article.
Loss of Dmrt5 results in decreased Wnt and Bmp in one of the major telencephalic patterning centers, the dorsomedial telencephalon, and in a reduction of Cajal-Retzius cells. ...Consistently, Dmrt5(-/-) brains exhibit patterning defects with a dramatic reduction of …
Loss of Dmrt5 results in decreased Wnt and Bmp in one of the major telencephalic patterning centers, the dorsomedial telencephalon, and in …
Effects of Emx2 inactivation on the gene expression profile of neural precursors.
Gangemi RM, Daga A, Muzio L, Marubbi D, Cocozza S, Perera M, Verardo S, Bordo D, Griffero F, Capra MC, Mallamaci A, Corte G. Gangemi RM, et al. Eur J Neurosci. 2006 Jan;23(2):325-34. doi: 10.1111/j.1460-9568.2005.04559.x. Eur J Neurosci. 2006. PMID: 16420441
Emx2 plays a crucial role in the development of the diencephalon and dorsal telencephalon. Thus, Emx2-null mutants have abnormal cortical lamination and a reduction in size of the caudal and medial areas of the prosencephalon. ...The gene expression profile suggeste …
Emx2 plays a crucial role in the development of the diencephalon and dorsal telencephalon. Thus, Emx2-null mutants have abnormal cort …
Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium.
Muzio L, Mallamaci A. Muzio L, et al. J Neurosci. 2005 Apr 27;25(17):4435-41. doi: 10.1523/JNEUROSCI.4804-04.2005. J Neurosci. 2005. PMID: 15858069 Free PMC article.
Being expressed along a rostral/lateral(high)- to-caudal/medial(low) gradient, Foxg1, moreover, could contribute to shaping the cortical areal profile as a repressor of caudomedial fates. ...Even if lacking a neocortical plate, Foxg1-/- embryos give rise to s …
Being expressed along a rostral/lateral(high)- to-caudal/medial(low) gradient, Foxg1, moreover, could contribute to shaping the corti …
Developmental control of cortico-cerebral astrogenesis.
Mallamaci A. Mallamaci A. Int J Dev Biol. 2013;57(9-10):689-706. doi: 10.1387/ijdb.130148am. Int J Dev Biol. 2013. PMID: 24307293 Review.
A remarkable body of research over the last 15 years has been aimed at disentangling the cellular and molecular mechanisms which regulate murine cortico-cerebral astrogenesis. ...The aim of this review is to provide a comprehensive and organic synthesis of these mec
A remarkable body of research over the last 15 years has been aimed at disentangling the cellular and molecular mechanisms which regu
RNA activation of haploinsufficient Foxg1 gene in murine neocortex.
Fimiani C, Goina E, Su Q, Gao G, Mallamaci A. Fimiani C, et al. Among authors: mallamaci a. Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311. Sci Rep. 2016. PMID: 27995975 Free PMC article.
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