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Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial.
Perahia DG, Wang F, Mallinckrodt CH, Walker DJ, Detke MJ. Perahia DG, et al. Among authors: mallinckrodt ch. Eur Psychiatry. 2006 Sep;21(6):367-78. doi: 10.1016/j.eurpsy.2006.03.004. Epub 2006 May 11. Eur Psychiatry. 2006. PMID: 16697153 Clinical Trial.
Duloxetine for the long-term treatment of major depressive disorder in patients aged 65 and older: an open-label study.
Wohlreich MM, Mallinckrodt CH, Watkin JG, Hay DP. Wohlreich MM, et al. Among authors: mallinckrodt ch. BMC Geriatr. 2004 Dec 7;4:11. doi: 10.1186/1471-2318-4-11. BMC Geriatr. 2004. PMID: 15585058 Free PMC article.
Duloxetine in the treatment of Major Depressive Disorder: a comparison of efficacy in patients with and without melancholic features.
Mallinckrodt CH, Watkin JG, Liu C, Wohlreich MM, Raskin J. Mallinckrodt CH, et al. BMC Psychiatry. 2005 Jan 4;5:1. doi: 10.1186/1471-244X-5-1. BMC Psychiatry. 2005. PMID: 15631624 Free PMC article.
Signal detection and placebo response in schizophrenia: parallels with depression.
Mallinckrodt CH, Zhang L, Prucka WR, Millen BA. Mallinckrodt CH, et al. Psychopharmacol Bull. 2010;43(1):53-72. Psychopharmacol Bull. 2010. PMID: 20581800
Addressing methodological issues in studying antidepressant onset efficacy using prespecified sensitivity analyses.
Lipkovich I, Mallinckrodt CH, Prakash A, Nierenberg AA. Lipkovich I, et al. Among authors: mallinckrodt ch. Psychopharmacol Bull. 2008;41(2):40-54. Psychopharmacol Bull. 2008. PMID: 18668016 Clinical Trial.
Simple options for improving signal detection in antidepressant clinical trials.
Mallinckrodt CH, Meyers AL, Prakash A, Faries DE, Detke MJ. Mallinckrodt CH, et al. Psychopharmacol Bull. 2007;40(2):101-14. Psychopharmacol Bull. 2007. PMID: 17514189
Assessing and interpreting treatment effects in longitudinal clinical trials with missing data.
Mallinckrodt CH, Sanger TM, Dubé S, DeBrota DJ, Molenberghs G, Carroll RJ, Potter WZ, Tollefson GD. Mallinckrodt CH, et al. Biol Psychiatry. 2003 Apr 15;53(8):754-60. doi: 10.1016/s0006-3223(02)01867-x. Biol Psychiatry. 2003. PMID: 12706959
A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy.
Kornstein SG, Dunner DL, Meyers AL, Whitmyer VG, Mallinckrodt CH, Wohlreich MM, Detke MJ, Hollandbeck MS, Greist JH. Kornstein SG, et al. Among authors: mallinckrodt ch. J Clin Psychiatry. 2008 Sep;69(9):1383-92. doi: 10.4088/jcp.v69n0905. J Clin Psychiatry. 2008. PMID: 19193339 Clinical Trial.
Recent developments in improving signal detection and reducing placebo response in psychiatric clinical trials.
Mallinckrodt CH, Tamura RN, Tanaka Y. Mallinckrodt CH, et al. J Psychiatr Res. 2011 Sep;45(9):1202-7. doi: 10.1016/j.jpsychires.2011.03.001. Epub 2011 Mar 31. J Psychiatr Res. 2011. PMID: 21453932
Duloxetine efficacy for major depressive disorder in male vs. female patients: data from 7 randomized, double-blind, placebo-controlled trials.
Kornstein SG, Wohlreich MM, Mallinckrodt CH, Watkin JG, Stewart DE. Kornstein SG, et al. Among authors: mallinckrodt ch. J Clin Psychiatry. 2006 May;67(5):761-70. doi: 10.4088/jcp.v67n0510. J Clin Psychiatry. 2006. PMID: 16841626
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