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Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.
Rosenzwajg M, Churlaud G, Mallone R, Six A, Dérian N, Chaara W, Lorenzon R, Long SA, Buckner JH, Afonso G, Pham HP, Hartemann A, Yu A, Pugliese A, Malek TR, Klatzmann D. Rosenzwajg M, et al. Among authors: mallone r. J Autoimmun. 2015 Apr;58:48-58. doi: 10.1016/j.jaut.2015.01.001. Epub 2015 Jan 26. J Autoimmun. 2015. PMID: 25634360 Free PMC article. Clinical Trial.
acDCs enhance human antigen-specific T-cell responses.
Martinuzzi E, Afonso G, Gagnerault MC, Naselli G, Mittag D, Combadière B, Boitard C, Chaput N, Zitvogel L, Harrison LC, Mallone R. Martinuzzi E, et al. Among authors: mallone r. Blood. 2011 Aug 25;118(8):2128-37. doi: 10.1182/blood-2010-12-326231. Epub 2011 Jun 28. Blood. 2011. PMID: 21715316 Free article.
Reduced naïve CD8(+) T-cell priming efficacy in elderly adults.
Briceño O, Lissina A, Wanke K, Afonso G, von Braun A, Ragon K, Miquel T, Gostick E, Papagno L, Stiasny K, Price DA, Mallone R, Sauce D, Karrer U, Appay V. Briceño O, et al. Among authors: mallone r. Aging Cell. 2016 Feb;15(1):14-21. doi: 10.1111/acel.12384. Epub 2015 Oct 15. Aging Cell. 2016. PMID: 26472076 Free PMC article.
Loss of immune tolerance to IL-2 in type 1 diabetes.
Pérol L, Lindner JM, Caudana P, Nunez NG, Baeyens A, Valle A, Sedlik C, Loirat D, Boyer O, Créange A, Cohen JL, Rogner UC, Yamanouchi J, Marchant M, Leber XC, Scharenberg M, Gagnerault MC, Mallone R, Battaglia M, Santamaria P, Hartemann A, Traggiai E, Piaggio E. Pérol L, et al. Among authors: mallone r. Nat Commun. 2016 Oct 6;7:13027. doi: 10.1038/ncomms13027. Nat Commun. 2016. PMID: 27708334 Free PMC article.
123 results