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Page 1
Assessment of Mycobacterium tuberculosis pantothenate kinase vulnerability through target knockdown and mechanistically diverse inhibitors.
Reddy BK, Landge S, Ravishankar S, Patil V, Shinde V, Tantry S, Kale M, Raichurkar A, Menasinakai S, Mudugal NV, Ambady A, Ghosh A, Tunduguru R, Kaur P, Singh R, Kumar N, Bharath S, Sundaram A, Bhat J, Sambandamurthy VK, Björkelid C, Jones TA, Das K, Bandodkar B, Malolanarasimhan K, Mukherjee K, Ramachandran V. Reddy BK, et al. Among authors: malolanarasimhan k. Antimicrob Agents Chemother. 2014 Jun;58(6):3312-26. doi: 10.1128/AAC.00140-14. Epub 2014 Mar 31. Antimicrob Agents Chemother. 2014. PMID: 24687493 Free PMC article.
Screening, identification, and characterization of mechanistically diverse inhibitors of the Mycobacterium tuberculosis enzyme, pantothenate kinase (CoaA).
Venkatraman J, Bhat J, Solapure SM, Sandesh J, Sarkar D, Aishwarya S, Mukherjee K, Datta S, Malolanarasimhan K, Bandodkar B, Das KS. Venkatraman J, et al. Among authors: malolanarasimhan k. J Biomol Screen. 2012 Mar;17(3):293-302. doi: 10.1177/1087057111423069. Epub 2011 Nov 15. J Biomol Screen. 2012. PMID: 22086722
Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.
Kale RR, Kale MG, Waterson D, Raichurkar A, Hameed SP, Manjunatha MR, Kishore Reddy BK, Malolanarasimhan K, Shinde V, Koushik K, Jena LK, Menasinakai S, Humnabadkar V, Madhavapeddi P, Basavarajappa H, Sharma S, Nandishaiah R, Mahesh Kumar KN, Ganguly S, Ahuja V, Gaonkar S, Naveen Kumar CN, Ogg D, Boriack-Sjodin PA, Sambandamurthy VK, de Sousa SM, Ghorpade SR. Kale RR, et al. Among authors: malolanarasimhan k. Bioorg Med Chem Lett. 2014 Feb 1;24(3):870-9. doi: 10.1016/j.bmcl.2013.12.080. Epub 2013 Dec 25. Bioorg Med Chem Lett. 2014. PMID: 24405701
Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.
Malolanarasimhan K, Kedei N, Sigano DM, Kelley JA, Lai CC, Lewin NE, Surawski RJ, Pavlyukovets VA, Garfield SH, Wincovitch S, Blumberg PM, Marquez VE. Malolanarasimhan K, et al. J Med Chem. 2007 Mar 8;50(5):962-78. doi: 10.1021/jm061289j. Epub 2007 Feb 7. J Med Chem. 2007. PMID: 17284021
Short synthesis of octosyl nucleosides.
Knapp S, Thakur VV, Madduru MR, Malolanarasimhan K, Morriello GJ, Doss GA. Knapp S, et al. Among authors: malolanarasimhan k. Org Lett. 2006 Mar 30;8(7):1335-7. doi: 10.1021/ol0600382. Org Lett. 2006. PMID: 16562885