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CDK4/6 Inhibitors resTORe Therapeutic Sensitivity in HER²⁺ Breast Cancer.
Malumbres M. Malumbres M. Cancer Cell. 2016 Mar 14;29(3):243-244. doi: 10.1016/j.ccell.2016.02.016. Cancer Cell. 2016. PMID: 26977873
Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice.
Mangues R, Corral T, Kohl NE, Symmans WF, Lu S, Malumbres M, Gibbs JB, Oliff A, Pellicer A. Mangues R, et al. Among authors: malumbres m. Cancer Res. 1998 Mar 15;58(6):1253-9. Cancer Res. 1998. PMID: 9515813
Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis.
Latres E, Malumbres M, Sotillo R, Martín J, Ortega S, Martín-Caballero J, Flores JM, Cordón-Cardo C, Barbacid M. Latres E, et al. Among authors: malumbres m. EMBO J. 2000 Jul 3;19(13):3496-506. doi: 10.1093/emboj/19.13.3496. EMBO J. 2000. PMID: 10880462 Free PMC article.
Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors.
Malumbres M, Ortega S, Barbacid M. Malumbres M, et al. Biol Chem. 2000 Sep-Oct;381(9-10):827-38. doi: 10.1515/BC.2000.105. Biol Chem. 2000. PMID: 11076015 Review.
Invasive melanoma in Cdk4-targeted mice.
Sotillo R, García JF, Ortega S, Martin J, Dubus P, Barbacid M, Malumbres M. Sotillo R, et al. Among authors: malumbres m. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13312-7. doi: 10.1073/pnas.241338598. Epub 2001 Oct 23. Proc Natl Acad Sci U S A. 2001. PMID: 11606789 Free PMC article.
., Hauer, M., Schneider, J., Serrano, M., Wolfel, C., et al. (1995) Science 269, 1281-1284; Zuo, L., Weger, J., Yang, Q., Goldstein, A. M., Tucker, M. A., et al. (1996) Nat. Genet. 12, 97-99). This mutation, R24C, renders the Cdk4 protein insensitive t …
., Hauer, M., Schneider, J., Serrano, M., Wolfel, C., et al. (1995) Science 269, 1281-1284; Zuo, L., Weger, J., Yang, Q., Gold …
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.
Sotillo R, Dubus P, Martín J, de la Cueva E, Ortega S, Malumbres M, Barbacid M. Sotillo R, et al. Among authors: malumbres m. EMBO J. 2001 Dec 3;20(23):6637-47. doi: 10.1093/emboj/20.23.6637. EMBO J. 2001. PMID: 11726500 Free PMC article.
To cycle or not to cycle: a critical decision in cancer.
Malumbres M, Barbacid M. Malumbres M, et al. Nat Rev Cancer. 2001 Dec;1(3):222-31. doi: 10.1038/35106065. Nat Rev Cancer. 2001. PMID: 11902577 Review.
Cyclin D-dependent kinases, INK4 inhibitors and cancer.
Ortega S, Malumbres M, Barbacid M. Ortega S, et al. Among authors: malumbres m. Biochim Biophys Acta. 2002 Mar 14;1602(1):73-87. doi: 10.1016/s0304-419x(02)00037-9. Biochim Biophys Acta. 2002. PMID: 11960696 Review.
RAS oncogenes: the first 30 years.
Malumbres M, Barbacid M. Malumbres M, et al. Nat Rev Cancer. 2003 Jun;3(6):459-65. doi: 10.1038/nrc1097. Nat Rev Cancer. 2003. PMID: 12778136 Review.
Driving the cell cycle to cancer.
Malumbres M, Hunt SL, Sotillo R, Martín J, Odajima J, Martín A, Dubus P, Ortega S, Barbacid M. Malumbres M, et al. Adv Exp Med Biol. 2003;532:1-11. doi: 10.1007/978-1-4615-0081-0_1. Adv Exp Med Biol. 2003. PMID: 12908544 Review.
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