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Purification and culture of corticospinal motor neurons.
Mandemakers W. Mandemakers W. Cold Spring Harb Protoc. 2014 Apr 1;2014(4):336-8. doi: 10.1101/pdb.top070938. Cold Spring Harb Protoc. 2014. PMID: 24692486 Review.
A novel purification method for CNS projection neurons leads to the identification of brain vascular cells as a source of trophic support for corticospinal motor neurons.
Dugas JC, Mandemakers W, Rogers M, Ibrahim A, Daneman R, Barres BA. Dugas JC, et al. Among authors: mandemakers w. J Neurosci. 2008 Aug 13;28(33):8294-305. doi: 10.1523/JNEUROSCI.2010-08.2008. J Neurosci. 2008. PMID: 18701692 Free PMC article.
Retrograde labeling of corticospinal motor neurons from early postnatal rodents.
Mandemakers W. Mandemakers W. Cold Spring Harb Protoc. 2014 Apr 1;2014(4):372-9. doi: 10.1101/pdb.prot074922. Cold Spring Harb Protoc. 2014. PMID: 24692490
LRRK2 expression is enriched in the striosomal compartment of mouse striatum.
Mandemakers W, Snellinx A, O'Neill MJ, de Strooper B. Mandemakers W, et al. Neurobiol Dis. 2012 Dec;48(3):582-93. doi: 10.1016/j.nbd.2012.07.017. Epub 2012 Jul 29. Neurobiol Dis. 2012. PMID: 22850484
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy.
Cornelissen T, Haddad D, Wauters F, Van Humbeeck C, Mandemakers W, Koentjoro B, Sue C, Gevaert K, De Strooper B, Verstreken P, Vandenberghe W. Cornelissen T, et al. Among authors: mandemakers w. Hum Mol Genet. 2014 Oct 1;23(19):5227-42. doi: 10.1093/hmg/ddu244. Epub 2014 May 22. Hum Mol Genet. 2014. PMID: 24852371 Free PMC article.
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice.
Papadopoulou AS, Serneels L, Achsel T, Mandemakers W, Callaerts-Vegh Z, Dooley J, Lau P, Ayoubi T, Radaelli E, Spinazzi M, Neumann M, H├ębert SS, Silahtaroglu A, Liston A, D'Hooge R, Glatzel M, De Strooper B. Papadopoulou AS, et al. Among authors: mandemakers w. Neurobiol Dis. 2015 Jan;73:275-88. doi: 10.1016/j.nbd.2014.10.006. Epub 2014 Oct 12. Neurobiol Dis. 2015. PMID: 25315682
Parkin interacts with Ambra1 to induce mitophagy.
Van Humbeeck C, Cornelissen T, Hofkens H, Mandemakers W, Gevaert K, De Strooper B, Vandenberghe W. Van Humbeeck C, et al. Among authors: mandemakers w. J Neurosci. 2011 Jul 13;31(28):10249-61. doi: 10.1523/JNEUROSCI.1917-11.2011. J Neurosci. 2011. PMID: 21753002 Free PMC article.
The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth.
Winzeler AM, Mandemakers WJ, Sun MZ, Stafford M, Phillips CT, Barres BA. Winzeler AM, et al. Among authors: mandemakers wj. J Neurosci. 2011 Apr 27;31(17):6481-92. doi: 10.1523/JNEUROSCI.3004-10.2011. J Neurosci. 2011. PMID: 21525289 Free PMC article.
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