Mandinova A - Search Results

1

Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: mandinova a. Nature. 2011 Jul 13;475(7355):231-4. doi: 10.1038/nature10167. Nature. 2011. PMID: 21753854 Free PMC article. Retracted.

2

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: mandinova a. Nature. 2018 Sep;561(7723):420. doi: 10.1038/s41586-018-0284-y. Nature. 2018. PMID: 30046103 Free PMC article.

3

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.

Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW. Gurkar AU, et al. Among authors: mandinova a. Nat Commun. 2013;4:2189. doi: 10.1038/ncomms3189. Nat Commun. 2013. PMID: 23877263 Free PMC article.

4

Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Raj L, et al. Among authors: mandinova a. Nature. 2015 Oct 22;526(7574):596. doi: 10.1038/nature15370. Epub 2015 Sep 16. Nature. 2015. PMID: 26375002 No abstract available.

5

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.

Hiraki M, Hwang SY, Cao S, Ramadhar TR, Byun S, Yoon KW, Lee JH, Chu K, Gurkar AU, Kolev V, Zhang J, Namba T, Murphy ME, Newman DJ, Mandinova A, Clardy J, Lee SW. Hiraki M, et al. Among authors: mandinova a. Chem Biol. 2015 Sep 17;22(9):1206-16. doi: 10.1016/j.chembiol.2015.07.016. Epub 2015 Aug 27. Chem Biol. 2015. PMID: 26320861 Free PMC article.

6

Emerging roles of p53 and other tumour-suppressor genes in immune regulation.

Muñoz-Fontela C, Mandinova A, Aaronson SA, Lee SW. Muñoz-Fontela C, et al. Among authors: mandinova a. Nat Rev Immunol. 2016 Dec;16(12):741-750. doi: 10.1038/nri.2016.99. Epub 2016 Sep 26. Nat Rev Immunol. 2016. PMID: 27667712 Free PMC article. Review.

7

A small molecule that binds Hedgehog and blocks its signaling in human cells.

Stanton BZ, Peng LF, Maloof N, Nakai K, Wang X, Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A, Schreiber SL. Stanton BZ, et al. Among authors: mandinova a. Nat Chem Biol. 2009 Mar;5(3):154-6. doi: 10.1038/nchembio.142. Epub 2009 Jan 18. Nat Chem Biol. 2009. PMID: 19151731 Free PMC article.

8

The p53 pathway as a target in cancer therapeutics: obstacles and promise.

Mandinova A, Lee SW. Mandinova A, et al. Sci Transl Med. 2011 Jan 5;3(64):64rv1. doi: 10.1126/scitranslmed.3001366. Sci Transl Med. 2011. PMID: 21209413 Free PMC article. Review.

9

Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling.

Hwang SY, Deng X, Byun S, Lee C, Lee SJ, Suh H, Zhang J, Kang Q, Zhang T, Westover KD, Mandinova A, Lee SW. Hwang SY, et al. Among authors: mandinova a. Cell Rep. 2016 Jun 28;16(1):28-36. doi: 10.1016/j.celrep.2016.05.071. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320923 Free PMC article.

10

DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.

Kim HG, Hwang SY, Aaronson SA, Mandinova A, Lee SW. Kim HG, et al. Among authors: mandinova a. J Biol Chem. 2011 May 20;286(20):17672-81. doi: 10.1074/jbc.M111.236612. Epub 2011 Mar 13. J Biol Chem. 2011. PMID: 21398698 Free PMC article. Retracted.

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