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Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities.
Huang LO, Rauch A, Mazzaferro E, Preuss M, Carobbio S, Bayrak CS, Chami N, Wang Z, Schick UM, Yang N, Itan Y, Vidal-Puig A, den Hoed M, Mandrup S, Kilpeläinen TO, Loos RJF. Huang LO, et al. Among authors: mandrup s. Nat Metab. 2021 Feb;3(2):228-243. doi: 10.1038/s42255-021-00346-2. Epub 2021 Feb 22. Nat Metab. 2021. PMID: 33619380
Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors.
Elholm M, Dam I, Jorgensen C, Krogsdam AM, Holst D, Kratchmarova I, Gottlicher M, Gustafsson JA, Berge R, Flatmark T, Knudsen J, Mandrup S, Kristiansen K. Elholm M, et al. Among authors: mandrup s. J Biol Chem. 2001 Jun 15;276(24):21410-6. doi: 10.1074/jbc.M101073200. Epub 2001 Feb 20. J Biol Chem. 2001. PMID: 11279171 Free article.
ACBP--a PPAR and SREBP modulated housekeeping gene.
Neess D, Kiilerich P, Sandberg MB, Helledie T, Nielsen R, Mandrup S. Neess D, et al. Among authors: mandrup s. Mol Cell Biochem. 2006 Mar;284(1-2):149-57. doi: 10.1007/s11010-005-9039-9. Epub 2006 Jan 13. Mol Cell Biochem. 2006. PMID: 16411019
151 results