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The role of interleukin-1 in the pathogenesis of IDDM.
Mandrup-Poulsen T. Mandrup-Poulsen T. Diabetologia. 1996 Sep;39(9):1005-29. doi: 10.1007/BF00400649. Diabetologia. 1996. PMID: 8877284 Review. No abstract available.
Mandrup-Poulsen T. Mandrup-Poulsen T. BMJ. 1998 Apr 18;316(7139):1221-5. doi: 10.1136/bmj.316.7139.1221. BMJ. 1998. PMID: 9553001 Free PMC article. Review. No abstract available.
Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice.
Besançon A, Goncalves T, Valette F, Dahllöf MS, Mandrup-Poulsen T, Chatenoud L, You S. Besançon A, et al. Diabetologia. 2018 Feb;61(2):389-398. doi: 10.1007/s00125-017-4459-0. Epub 2017 Oct 13. Diabetologia. 2018. PMID: 29030662
No direct effect of SGLT2 activity on glucagon secretion.
Kuhre RE, Ghiasi SM, Adriaenssens AE, Wewer Albrechtsen NJ, Andersen DB, Aivazidis A, Chen L, Mandrup-Poulsen T, Ørskov C, Gribble FM, Reimann F, Wierup N, Tyrberg B, Holst JJ. Kuhre RE, et al. Diabetologia. 2019 Jun;62(6):1011-1023. doi: 10.1007/s00125-019-4849-6. Epub 2019 Mar 22. Diabetologia. 2019. PMID: 30903205 Free PMC article.
Cytokines and beta-cell biology: from concept to clinical translation.
Donath MY, Størling J, Berchtold LA, Billestrup N, Mandrup-Poulsen T. Donath MY, et al. Endocr Rev. 2008 May;29(3):334-50. doi: 10.1210/er.2007-0033. Epub 2007 Nov 29. Endocr Rev. 2008. PMID: 18048762 Review.
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.
Lindeløv Vestergaard A, Heiner Bang-Berthelsen C, Fløyel T, Lucien Stahl J, Christen L, Taheri Sotudeh F, de Hemmer Horskjær P, Stensgaard Frederiksen K, Greek Kofod F, Bruun C, Adrian Berchtold L, Størling J, Regazzi R, Kaur S, Pociot F, Mandrup-Poulsen T. Lindeløv Vestergaard A, et al. PLoS One. 2018 Sep 27;13(9):e0203713. doi: 10.1371/journal.pone.0203713. eCollection 2018. PLoS One. 2018. PMID: 30260972 Free PMC article.
Inhibition of beta cell growth and function by bone morphogenetic proteins.
Bruun C, Christensen GL, Jacobsen ML, Kanstrup MB, Jensen PR, Fjordvang H, Mandrup-Poulsen T, Billestrup N. Bruun C, et al. Diabetologia. 2014 Dec;57(12):2546-54. doi: 10.1007/s00125-014-3384-8. Epub 2014 Sep 27. Diabetologia. 2014. PMID: 25260823
Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex.
Frobøse H, Rønn SG, Heding PE, Mendoza H, Cohen P, Mandrup-Poulsen T, Billestrup N. Frobøse H, et al. Mol Endocrinol. 2006 Jul;20(7):1587-96. doi: 10.1210/me.2005-0301. Epub 2006 Mar 16. Mol Endocrinol. 2006. PMID: 16543409
Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.
Størling J, Zaitsev SV, Kapelioukh IL, Karlsen AE, Billestrup N, Berggren PO, Mandrup-Poulsen T. Størling J, et al. Endocrinology. 2005 Jul;146(7):3026-36. doi: 10.1210/en.2005-0036. Epub 2005 Apr 14. Endocrinology. 2005. PMID: 15831571
Beta cell death and protection.
Mandrup-Poulsen T. Mandrup-Poulsen T. Ann N Y Acad Sci. 2003 Nov;1005:32-42. doi: 10.1196/annals.1288.005. Ann N Y Acad Sci. 2003. PMID: 14679038 Review.
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