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AAV9: a potential blood-brain barrier buster.
Manfredsson FP, Rising AC, Mandel RJ. Manfredsson FP, et al. Mol Ther. 2009 Mar;17(3):403-5. doi: 10.1038/mt.2009.15. Mol Ther. 2009. PMID: 19247366 Free PMC article. No abstract available.
Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model.
Gombash SE, Lipton JW, Collier TJ, Madhavan L, Steece-Collier K, Cole-Strauss A, Terpstra BT, Spieles-Engemann AL, Daley BF, Wohlgenant SL, Thompson VB, Manfredsson FP, Mandel RJ, Sortwell CE. Gombash SE, et al. Among authors: manfredsson fp. Mol Ther. 2012 Mar;20(3):544-54. doi: 10.1038/mt.2011.216. Epub 2011 Oct 18. Mol Ther. 2012. PMID: 22008908 Free PMC article.
Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS.
Kanaan NM, Sellnow RC, Boye SL, Coberly B, Bennett A, Agbandje-McKenna M, Sortwell CE, Hauswirth WW, Boye SE, Manfredsson FP. Kanaan NM, et al. Among authors: manfredsson fp. Mol Ther Nucleic Acids. 2017 Sep 15;8:184-197. doi: 10.1016/j.omtn.2017.06.011. Epub 2017 Jun 21. Mol Ther Nucleic Acids. 2017. PMID: 28918020 Free PMC article.
In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration.
Gorbatyuk OS, Li S, Nash K, Gorbatyuk M, Lewin AS, Sullivan LF, Mandel RJ, Chen W, Meyers C, Manfredsson FP, Muzyczka N. Gorbatyuk OS, et al. Among authors: manfredsson fp. Mol Ther. 2010 Aug;18(8):1450-7. doi: 10.1038/mt.2010.115. Epub 2010 Jun 15. Mol Ther. 2010. PMID: 20551914 Free PMC article.
85 results