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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1861 1
1888 1
1889 1
1897 1
1908 1
1916 1
1918 2
1919 2
1921 2
1922 3
1923 4
1925 3
1926 2
1927 3
1928 2
1929 3
1930 5
1931 4
1932 2
1933 1
1935 2
1937 1
1938 1
1939 6
1940 2
1941 4
1942 2
1944 1
1945 6
1946 17
1947 32
1948 19
1949 24
1950 30
1951 24
1952 19
1953 36
1954 45
1955 36
1956 29
1957 39
1958 31
1959 35
1960 26
1961 47
1962 54
1963 107
1964 203
1965 113
1966 74
1967 98
1968 101
1969 108
1970 101
1971 82
1972 108
1973 129
1974 119
1975 182
1976 166
1977 186
1978 182
1979 204
1980 209
1981 241
1982 214
1983 238
1984 269
1985 265
1986 269
1987 265
1988 239
1989 275
1990 304
1991 313
1992 315
1993 339
1994 387
1995 405
1996 458
1997 436
1998 498
1999 522
2000 585
2001 712
2002 727
2003 757
2004 907
2005 1023
2006 1047
2007 1147
2008 1227
2009 1270
2010 1336
2011 1582
2012 1472
2013 1593
2014 1742
2015 1855
2016 1840
2017 1946
2018 2097
2019 2259
2020 2429
2021 2703
2022 2792
2023 446
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40,321 results
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Page 1
The role of manganese dysregulation in neurological disease: emerging evidence.
Budinger D, Barral S, Soo AKS, Kurian MA. Budinger D, et al. Lancet Neurol. 2021 Nov;20(11):956-968. doi: 10.1016/S1474-4422(21)00238-6. Lancet Neurol. 2021. PMID: 34687639 Review.
Manganese is an essential trace metal. The dysregulation of manganese seen in a broad spectrum of neurological disorders reflects its importance in brain development and key neurophysiological processes. Historically, the observation of acquired manganism in miners …
Manganese is an essential trace metal. The dysregulation of manganese seen in a broad spectrum of neurological disorders refle …
Manganese-driven CoQ deficiency.
Diessl J, Berndtsson J, Broeskamp F, Habernig L, Kohler V, Vazquez-Calvo C, Nandy A, Peselj C, Drobysheva S, Pelosi L, Vögtle FN, Pierrel F, Ott M, Büttner S. Diessl J, et al. Nat Commun. 2022 Oct 13;13(1):6061. doi: 10.1038/s41467-022-33641-x. Nat Commun. 2022. PMID: 36229432 Free PMC article.
Overexposure to manganese disrupts cellular energy metabolism across species, but the molecular mechanism underlying manganese toxicity remains enigmatic. Here, we report that excess cellular manganese selectively disrupts coenzyme Q (CoQ) biosynthesis, resul …
Overexposure to manganese disrupts cellular energy metabolism across species, but the molecular mechanism underlying manganese …
Manganese-Catalyzed Hydrosilylation Reactions.
Yang X, Wang C. Yang X, et al. Chem Asian J. 2018 Sep 4;13(17):2307-2315. doi: 10.1002/asia.201800618. Epub 2018 Jul 16. Chem Asian J. 2018. PMID: 29781172 Review.
Over the past few decades, manganese-catalyzed hydrosilylation of C=O or C=C/CC unsaturated bonds have undergone enormous developments. In this focus review, the hydrosilylation reactions of alkenes, alkynes, and carbonyl-containing substrates catalyzed by manganese …
Over the past few decades, manganese-catalyzed hydrosilylation of C=O or C=C/CC unsaturated bonds have undergone enormous development …
Manganese.
Barceloux DG. Barceloux DG. J Toxicol Clin Toxicol. 1999;37(2):293-307. doi: 10.1081/clt-100102427. J Toxicol Clin Toxicol. 1999. PMID: 10382563 Review.
Homeostatic mechanisms limit the absorption of manganese from the gastrointestinal tract. Elimination of manganese occurs primarily by excretion into the bile. ...The American Conference of Governmental and Industrial Hygienists recently lowered the TLV-TWA for m …
Homeostatic mechanisms limit the absorption of manganese from the gastrointestinal tract. Elimination of manganese occurs prim …
Manganese neurotoxicity.
Dobson AW, Erikson KM, Aschner M. Dobson AW, et al. Ann N Y Acad Sci. 2004 Mar;1012:115-28. doi: 10.1196/annals.1306.009. Ann N Y Acad Sci. 2004. PMID: 15105259 Review.
Manganese is an essential trace element and it is required for many ubiquitous enzymatic reactions. While manganese deficiency rarely occurs in humans, manganese toxicity is known to occur in certain occupational settings through inhalation of manganese …
Manganese is an essential trace element and it is required for many ubiquitous enzymatic reactions. While manganese deficiency …
Molecular physiology of manganese in insects.
Pankau C, Cooper RL. Pankau C, et al. Curr Opin Insect Sci. 2022 Jun;51:100886. doi: 10.1016/j.cois.2022.100886. Epub 2022 Mar 9. Curr Opin Insect Sci. 2022. PMID: 35278758 Review.
Given the significant function of manganese in insects, agriculture, and human disease, as well as in the healthy ecology of the planet, the biological activities of manganese in insects needs consideration. Because of the role of manganese as a cofactor for …
Given the significant function of manganese in insects, agriculture, and human disease, as well as in the healthy ecology of the plan …
Genetic Disorders of Manganese Metabolism.
Anagianni S, Tuschl K. Anagianni S, et al. Curr Neurol Neurosci Rep. 2019 May 14;19(6):33. doi: 10.1007/s11910-019-0942-y. Curr Neurol Neurosci Rep. 2019. PMID: 31089831 Free PMC article. Review.
PURPOSE OF REVIEW: This article provides an overview of the pathogenesis, clinical presentation and treatment of inherited manganese transporter defects. RECENT FINDINGS: Identification of a new group of manganese transportopathies has greatly advanced our understan …
PURPOSE OF REVIEW: This article provides an overview of the pathogenesis, clinical presentation and treatment of inherited manganese …
Inherited Disorders of Manganese Metabolism.
Zogzas CE, Mukhopadhyay S. Zogzas CE, et al. Adv Neurobiol. 2017;18:35-49. doi: 10.1007/978-3-319-60189-2_3. Adv Neurobiol. 2017. PMID: 28889262 Review.
While the neurotoxic effects of manganese were recognized in 1837, the first genetic disorder of manganese metabolism was described only in 2012 when homozygous mutations in SLC30A10 were reported to cause manganese-induced neurotoxicity. Two other genetic di …
While the neurotoxic effects of manganese were recognized in 1837, the first genetic disorder of manganese metabolism was desc …
Competition for Manganese at the Host-Pathogen Interface.
Kelliher JL, Kehl-Fie TE. Kelliher JL, et al. Prog Mol Biol Transl Sci. 2016;142:1-25. doi: 10.1016/bs.pmbts.2016.05.002. Epub 2016 Jun 20. Prog Mol Biol Transl Sci. 2016. PMID: 27571690 Review.
During infection, the host uses several mechanisms to impose manganese limitation. These include removal of manganese from the phagolysosome, sequestration of extracellular manganese, and utilization of other metals to prevent bacterial acquisition of mang …
During infection, the host uses several mechanisms to impose manganese limitation. These include removal of manganese from the …
Managing Manganese: The Role of Manganese Homeostasis in Streptococcal Pathogenesis.
Aggarwal S, Kumaraswami M. Aggarwal S, et al. Front Cell Dev Biol. 2022 Jun 21;10:921920. doi: 10.3389/fcell.2022.921920. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35800897 Free PMC article. Review.
Emerging evidence suggests that pathogens also encounter manganese toxicity during infection and manganese excess impacts streptococcal virulence by manganese mismetallation of non-cognate molecular targets involved in bacterial antioxidant defenses and cell …
Emerging evidence suggests that pathogens also encounter manganese toxicity during infection and manganese excess impacts stre …
40,321 results
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