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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1861 1
1888 1
1889 1
1908 1
1916 1
1918 2
1919 2
1921 2
1922 3
1923 4
1925 3
1926 2
1927 3
1928 2
1929 3
1930 5
1931 4
1932 2
1933 1
1935 2
1937 1
1938 1
1939 6
1940 2
1941 4
1942 2
1944 1
1945 6
1946 17
1947 32
1948 19
1949 24
1950 30
1951 24
1952 19
1953 36
1954 45
1955 36
1956 29
1957 39
1958 31
1959 35
1960 26
1961 47
1962 54
1963 107
1964 203
1965 113
1966 74
1967 97
1968 101
1969 108
1970 101
1971 82
1972 108
1973 129
1974 119
1975 182
1976 166
1977 186
1978 182
1979 203
1980 209
1981 241
1982 214
1983 238
1984 269
1985 265
1986 268
1987 265
1988 239
1989 275
1990 304
1991 313
1992 315
1993 339
1994 387
1995 405
1996 458
1997 436
1998 498
1999 521
2000 585
2001 711
2002 726
2003 757
2004 906
2005 1023
2006 1047
2007 1147
2008 1227
2009 1270
2010 1336
2011 1582
2012 1472
2013 1593
2014 1737
2015 1854
2016 1834
2017 1932
2018 2047
2019 2193
2020 2355
2021 1336
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36,175 results
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Page 1
Genetic Disorders of Manganese Metabolism.
Anagianni S, Tuschl K. Anagianni S, et al. Curr Neurol Neurosci Rep. 2019 May 14;19(6):33. doi: 10.1007/s11910-019-0942-y. Curr Neurol Neurosci Rep. 2019. PMID: 31089831 Free PMC article. Review.
PURPOSE OF REVIEW: This article provides an overview of the pathogenesis, clinical presentation and treatment of inherited manganese transporter defects. RECENT FINDINGS: Identification of a new group of manganese transportopathies has greatly advanced our understan …
PURPOSE OF REVIEW: This article provides an overview of the pathogenesis, clinical presentation and treatment of inherited manganese …
The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis.
Winslow JWW, Limesand KH, Zhao N. Winslow JWW, et al. Int J Mol Sci. 2020 May 7;21(9):3304. doi: 10.3390/ijms21093304. Int J Mol Sci. 2020. PMID: 32392784 Free PMC article. Review.
Therefore, manganese balance needs to be tightly controlled. In the past eight years, mutations of genes encoding metal transporters ZIP8 (SLC39A8), ZIP14 (SLC39A14), and ZnT10 (SLC30A10) have been identified to cause dysregulated manganese homeostasis in humans, hi …
Therefore, manganese balance needs to be tightly controlled. In the past eight years, mutations of genes encoding metal transporters …
Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia.
Tuschl K, Meyer E, Valdivia LE, Zhao N, Dadswell C, Abdul-Sada A, Hung CY, Simpson MA, Chong WK, Jacques TS, Woltjer RL, Eaton S, Gregory A, Sanford L, Kara E, Houlden H, Cuno SM, Prokisch H, Valletta L, Tiranti V, Younis R, Maher ER, Spencer J, Straatman-Iwanowska A, Gissen P, Selim LA, Pintos-Morell G, Coroleu-Lletget W, Mohammad SS, Yoganathan S, Dale RC, Thomas M, Rihel J, Bodamer OA, Enns CA, Hayflick SJ, Clayton PT, Mills PB, Kurian MA, Wilson SW. Tuschl K, et al. Nat Commun. 2016 May 27;7:11601. doi: 10.1038/ncomms11601. Nat Commun. 2016. PMID: 27231142 Free PMC article.
Although manganese is an essential trace metal, little is known about its transport and homeostatic regulation. ...We show that mutations in SLC39A14 impair manganese transport in vitro and lead to manganese dyshomeostasis and altered locomotor activity in ze …
Although manganese is an essential trace metal, little is known about its transport and homeostatic regulation. ...We show that mutat …
Manganese.
Barceloux DG. Barceloux DG. J Toxicol Clin Toxicol. 1999;37(2):293-307. doi: 10.1081/clt-100102427. J Toxicol Clin Toxicol. 1999. PMID: 10382563 Review.
Homeostatic mechanisms limit the absorption of manganese from the gastrointestinal tract. Elimination of manganese occurs primarily by excretion into the bile. ...The American Conference of Governmental and Industrial Hygienists recently lowered the TLV-TWA for m …
Homeostatic mechanisms limit the absorption of manganese from the gastrointestinal tract. Elimination of manganese occurs prim …
Inherited Disorders of Manganese Metabolism.
Zogzas CE, Mukhopadhyay S. Zogzas CE, et al. Adv Neurobiol. 2017;18:35-49. doi: 10.1007/978-3-319-60189-2_3. Adv Neurobiol. 2017. PMID: 28889262 Review.
While the neurotoxic effects of manganese were recognized in 1837, the first genetic disorder of manganese metabolism was described only in 2012 when homozygous mutations in SLC30A10 were reported to cause manganese-induced neurotoxicity. Two other genetic di …
While the neurotoxic effects of manganese were recognized in 1837, the first genetic disorder of manganese metabolism was desc …
How manganese empowered life with dioxygen (and vice versa).
Lingappa UF, Monteverde DR, Magyar JS, Valentine JS, Fischer WW. Lingappa UF, et al. Free Radic Biol Med. 2019 Aug 20;140:113-125. doi: 10.1016/j.freeradbiomed.2019.01.036. Epub 2019 Feb 7. Free Radic Biol Med. 2019. PMID: 30738765 Review.
Subsequently, the presence of O(2) transformed the biogeochemical dynamics of the manganese cycle, enabling a rich suite of environmental and biological processes involving high-valent manganese and manganese redox cycling. Here, we describe insights from che …
Subsequently, the presence of O(2) transformed the biogeochemical dynamics of the manganese cycle, enabling a rich suite of environme …
Manganese neurotoxicity.
Dobson AW, Erikson KM, Aschner M. Dobson AW, et al. Ann N Y Acad Sci. 2004 Mar;1012:115-28. doi: 10.1196/annals.1306.009. Ann N Y Acad Sci. 2004. PMID: 15105259 Review.
Manganese is an essential trace element and it is required for many ubiquitous enzymatic reactions. While manganese deficiency rarely occurs in humans, manganese toxicity is known to occur in certain occupational settings through inhalation of manganese …
Manganese is an essential trace element and it is required for many ubiquitous enzymatic reactions. While manganese deficiency …
Manganese-Catalyzed Hydrosilylation Reactions.
Yang X, Wang C. Yang X, et al. Chem Asian J. 2018 Sep 4;13(17):2307-2315. doi: 10.1002/asia.201800618. Epub 2018 Jul 16. Chem Asian J. 2018. PMID: 29781172 Review.
Over the past few decades, manganese-catalyzed hydrosilylation of C=O or C=C/CC unsaturated bonds have undergone enormous developments. In this focus review, the hydrosilylation reactions of alkenes, alkynes, and carbonyl-containing substrates catalyzed by manganese …
Over the past few decades, manganese-catalyzed hydrosilylation of C=O or C=C/CC unsaturated bonds have undergone enormous development …
Biomedical application of manganese dioxide nanomaterials.
Chen Y, Cong H, Shen Y, Yu B. Chen Y, et al. Nanotechnology. 2020 May 15;31(20):202001. doi: 10.1088/1361-6528/ab6fe1. Epub 2020 Jan 24. Nanotechnology. 2020. PMID: 31978932
Manganese dioxide nanomaterials are mainly used as drug carriers in tumor therapy. ...Manganese dioxide has also been used to quench fluorescent carbon dots in fluorescent probes. ...
Manganese dioxide nanomaterials are mainly used as drug carriers in tumor therapy. ...Manganese dioxide has also been used to …
Intestinal response to dietary manganese depletion in Drosophila.
Vásquez-Procopio J, Osorio B, Cortés-Martínez L, Hernández-Hernández F, Medina-Contreras O, Ríos-Castro E, Comjean A, Li F, Hu Y, Mohr S, Perrimon N, Missirlis F. Vásquez-Procopio J, et al. Metallomics. 2020 Feb 1;12(2):218-240. doi: 10.1039/c9mt00218a. Epub 2019 Dec 4. Metallomics. 2020. PMID: 31799578
To test the requirement of dietary manganese for this accumulation, we generated a Drosophila model of manganese deficiency. ...Dietary manganese depletion reduced Sod2 activity. We then examined gene and protein expression changes in the intestines of man …
To test the requirement of dietary manganese for this accumulation, we generated a Drosophila model of manganese deficiency. . …
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