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205 results
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In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue.
Houten SM, Volle DH, Cummins CL, Mangelsdorf DJ, Auwerx J. Houten SM, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2007 Jun;21(6):1312-23. doi: 10.1210/me.2007-0113. Epub 2007 Apr 10. Mol Endocrinol. 2007. PMID: 17426284
Nuclear receptor LRH-1 induces the reproductive neuropeptide kisspeptin in the hypothalamus.
Atkin SD, Owen BM, Bookout AL, Cravo RM, Lee C, Elias CF, Elmquist JK, Kliewer SA, Mangelsdorf DJ. Atkin SD, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2013 Apr;27(4):598-605. doi: 10.1210/me.2012-1371. Epub 2013 Mar 15. Mol Endocrinol. 2013. PMID: 23504956 Free PMC article.
Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer.
Jeong Y, Xie Y, Lee W, Bookout AL, Girard L, Raso G, Behrens C, Wistuba II, Gadzar AF, Minna JD, Mangelsdorf DJ. Jeong Y, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2012 Aug;26(8):1443-54. doi: 10.1210/me.2011-1382. Epub 2012 Jun 14. Mol Endocrinol. 2012. PMID: 22700587 Free PMC article.
Commentary: the year in nuclear receptor control of metabolism.
Mangelsdorf DJ. Mangelsdorf DJ. Mol Endocrinol. 2010 Nov;24(11):2075-80. doi: 10.1210/me.2010-0357. Epub 2010 Sep 29. Mol Endocrinol. 2010. PMID: 20880985 Free PMC article.
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.
McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. McKenna NJ, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2009 Jun;23(6):740-6. doi: 10.1210/me.2009-0135. Epub 2009 May 7. Mol Endocrinol. 2009. PMID: 19423650 Free PMC article. Review.
Expression profiling of nuclear receptors in human and mouse embryonic stem cells.
Xie CQ, Jeong Y, Fu M, Bookout AL, Garcia-Barrio MT, Sun T, Kim BH, Xie Y, Root S, Zhang J, Xu RH, Chen YE, Mangelsdorf DJ. Xie CQ, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2009 May;23(5):724-33. doi: 10.1210/me.2008-0465. Epub 2009 Feb 5. Mol Endocrinol. 2009. PMID: 19196830 Free PMC article.
Synthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor.
Sharma KK, Wang Z, Motola DL, Cummins CL, Mangelsdorf DJ, Auchus RJ. Sharma KK, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2009 May;23(5):640-8. doi: 10.1210/me.2008-0415. Epub 2009 Feb 5. Mol Endocrinol. 2009. PMID: 19196833 Free PMC article.
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling.
Gerisch B, Rottiers V, Li D, Motola DL, Cummins CL, Lehrach H, Mangelsdorf DJ, Antebi A. Gerisch B, et al. Among authors: mangelsdorf dj. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5014-9. doi: 10.1073/pnas.0700847104. Epub 2007 Mar 14. Proc Natl Acad Sci U S A. 2007. PMID: 17360327 Free PMC article.
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.
Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. Lee YK, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6. Mol Endocrinol. 2008. PMID: 18323469 Free PMC article.
FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption.
Jung D, Inagaki T, Gerard RD, Dawson PA, Kliewer SA, Mangelsdorf DJ, Moschetta A. Jung D, et al. Among authors: mangelsdorf dj. J Lipid Res. 2007 Dec;48(12):2693-700. doi: 10.1194/jlr.M700351-JLR200. Epub 2007 Sep 6. J Lipid Res. 2007. PMID: 17823457
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