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Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.
DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. DeVree BT, et al. Among authors: manglik a. Nature. 2016 Jul 7;535(7610):182-6. doi: 10.1038/nature18324. Epub 2016 Jun 29. Nature. 2016. PMID: 27362234 Free PMC article.
Structure of the δ-opioid receptor bound to naltrindole.
Granier S, Manglik A, Kruse AC, Kobilka TS, Thian FS, Weis WI, Kobilka BK. Granier S, et al. Among authors: manglik a. Nature. 2012 May 16;485(7398):400-4. doi: 10.1038/nature11111. Nature. 2012. PMID: 22596164 Free PMC article.
The dynamic process of β(2)-adrenergic receptor activation.
Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. Nygaard R, et al. Among authors: manglik a. Cell. 2013 Jan 31;152(3):532-42. doi: 10.1016/j.cell.2013.01.008. Cell. 2013. PMID: 23374348 Free PMC article.
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ. Shukla AK, et al. Among authors: manglik a. Nature. 2013 May 2;497(7447):137-41. doi: 10.1038/nature12120. Epub 2013 Apr 21. Nature. 2013. PMID: 23604254 Free PMC article.
Applications of molecular replacement to G protein-coupled receptors.
Kruse AC, Manglik A, Kobilka BK, Weis WI. Kruse AC, et al. Among authors: manglik a. Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2287-92. doi: 10.1107/S090744491301322X. Epub 2013 Oct 18. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 24189241 Free PMC article.
Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Kruse AC, Ring AM, Manglik A, Hu J, Hu K, Eitel K, Hübner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, Garcia KC, Wess J, Kobilka BK. Kruse AC, et al. Among authors: manglik a. Nature. 2013 Dec 5;504(7478):101-6. doi: 10.1038/nature12735. Epub 2013 Nov 20. Nature. 2013. PMID: 24256733 Free PMC article.
75 results