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Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Cummins CL, Mangravite LM, Benet LZ. Cummins CL, et al. Among authors: mangravite lm. Pharm Res. 2001 Aug;18(8):1102-9. doi: 10.1023/a:1010914624111. Pharm Res. 2001. PMID: 11587480
PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1.
Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM. Shu Y, et al. Among authors: mangravite lm. Pharmacol Rev. 2004 Jun;56(2):161. doi: 10.1124/pr.56.2.2. Pharmacol Rev. 2004. PMID: 15169925 No abstract available.
Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney.
Mangravite LM, Badagnani I, Giacomini KM. Mangravite LM, et al. Eur J Pharmacol. 2003 Oct 31;479(1-3):269-81. doi: 10.1016/j.ejphar.2003.08.076. Eur J Pharmacol. 2003. PMID: 14612157 Review.
Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1.
Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM; Pharmacogenetics Of Membrane Transporters Investigators. Shu Y, et al. Among authors: mangravite lm. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5902-7. doi: 10.1073/pnas.0730858100. Epub 2003 Apr 28. Proc Natl Acad Sci U S A. 2003. PMID: 12719534 Free PMC article.
Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells.
Mangravite LM, Xiao G, Giacomini KM. Mangravite LM, et al. Am J Physiol Renal Physiol. 2003 May;284(5):F902-10. doi: 10.1152/ajprenal.00215.2002. Epub 2003 Jan 14. Am J Physiol Renal Physiol. 2003. PMID: 12527552
Sorting of rat SPNT in renal epithelium is independent of N-glycosylation.
Mangravite LM, Giacomini KM. Mangravite LM, et al. Pharm Res. 2003 Feb;20(2):319-23. doi: 10.1023/a:1022247826750. Pharm Res. 2003. PMID: 12636174
Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line.
Mangravite LM, Lipschutz JH, Mostov KE, Giacomini KM. Mangravite LM, et al. Am J Physiol Renal Physiol. 2001 May;280(5):F879-85. doi: 10.1152/ajprenal.2001.280.5.F879. Am J Physiol Renal Physiol. 2001. PMID: 11292631
Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells.
Shu Y, Bello CL, Mangravite LM, Feng B, Giacomini KM. Shu Y, et al. Among authors: mangravite lm. J Pharmacol Exp Ther. 2001 Oct;299(1):392-8. J Pharmacol Exp Ther. 2001. PMID: 11561104
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins.
Ruby MA, Nomura DK, Hudak CS, Mangravite LM, Chiu S, Casida JE, Krauss RM. Ruby MA, et al. Among authors: mangravite lm. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14561-6. doi: 10.1073/pnas.0807232105. Epub 2008 Sep 15. Proc Natl Acad Sci U S A. 2008. PMID: 18794527 Free PMC article.
The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.
Erdman AR, Mangravite LM, Urban TJ, Lagpacan LL, Castro RA, de la Cruz M, Chan W, Huang CC, Johns SJ, Kawamoto M, Stryke D, Taylor TR, Carlson EJ, Ferrin TE, Brett CM, Burchard EG, Giacomini KM. Erdman AR, et al. Among authors: mangravite lm. Am J Physiol Renal Physiol. 2006 Apr;290(4):F905-12. doi: 10.1152/ajprenal.00272.2005. Epub 2005 Nov 15. Am J Physiol Renal Physiol. 2006. PMID: 16291576
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