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Genome-wide association of lipid-lowering response to statins in combined study populations.
Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM. Barber MJ, et al. Among authors: mangravite lm. PLoS One. 2010 Mar 22;5(3):e9763. doi: 10.1371/journal.pone.0009763. PLoS One. 2010. PMID: 20339536 Free PMC article. Clinical Trial.
Pharmacogenomics of statin response.
Mangravite LM, Krauss RM. Mangravite LM, et al. Curr Opin Lipidol. 2007 Aug;18(4):409-14. doi: 10.1097/MOL.0b013e328235a5a2. Curr Opin Lipidol. 2007. PMID: 17620857 Review.
Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.
Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI. Krauss RM, et al. Among authors: mangravite lm. Circulation. 2008 Mar 25;117(12):1537-44. doi: 10.1161/CIRCULATIONAHA.107.708388. Epub 2008 Mar 10. Circulation. 2008. PMID: 18332269
Pharmacogenomics of statin response.
Mangravite LM, Wilke RA, Zhang J, Krauss RM. Mangravite LM, et al. Curr Opin Mol Ther. 2008 Dec;10(6):555-61. Curr Opin Mol Ther. 2008. PMID: 19051133 Review.
RHOA is a modulator of the cholesterol-lowering effects of statin.
Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. Medina MW, et al. Among authors: mangravite lm. PLoS Genet. 2012;8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166513 Free PMC article.
Mangravite et al. reply.
Mangravite LM, Engelhardt BE, Stephens M, Krauss RM. Mangravite LM, et al. Nature. 2014 Sep 18;513(7518):E3. doi: 10.1038/nature13630. Nature. 2014. PMID: 25230670 No abstract available.
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM. Mangravite LM, et al. Nature. 2013 Oct 17;502(7471):377-80. doi: 10.1038/nature12508. Epub 2013 Aug 28. Nature. 2013. PMID: 23995691 Free PMC article.
Clinical implications of pharmacogenomics of statin treatment.
Mangravite LM, Thorn CF, Krauss RM. Mangravite LM, et al. Pharmacogenomics J. 2006 Nov-Dec;6(6):360-74. doi: 10.1038/sj.tpj.6500384. Epub 2006 Mar 21. Pharmacogenomics J. 2006. PMID: 16550210 Review. No abstract available.
101 results