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On the road from classical to modern molecular biology.
Maniatis T. Maniatis T. Nat Med. 2012 Oct;18(10):1499-502. doi: 10.1038/nm.2931. Nat Med. 2012. PMID: 23042362 No abstract available.
Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development.
Rizvi AH, Camara PG, Kandror EK, Roberts TJ, Schieren I, Maniatis T, Rabadan R. Rizvi AH, et al. Nat Biotechnol. 2017 Jun;35(6):551-560. doi: 10.1038/nbt.3854. Epub 2017 May 1. Nat Biotechnol. 2017. PMID: 28459448 Free PMC article.
Visualization of clustered protocadherin neuronal self-recognition complexes.
Brasch J, Goodman KM, Noble AJ, Rapp M, Mannepalli S, Bahna F, Dandey VP, Bepler T, Berger B, Maniatis T, Potter CS, Carragher B, Honig B, Shapiro L. Brasch J, et al. Among authors: maniatis t. Nature. 2019 May;569(7755):280-283. doi: 10.1038/s41586-019-1089-3. Epub 2019 Apr 10. Nature. 2019. PMID: 30971825 Free PMC article.
Proteolytic processing of protocadherin proteins requires endocytosis.
Buchanan SM, Schalm SS, Maniatis T. Buchanan SM, et al. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17774-9. doi: 10.1073/pnas.1013105107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876099 Free PMC article.
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts.
McWhirter SM, Fitzgerald KA, Rosains J, Rowe DC, Golenbock DT, Maniatis T. McWhirter SM, et al. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):233-8. doi: 10.1073/pnas.2237236100. Epub 2003 Dec 16. Proc Natl Acad Sci U S A. 2004. PMID: 14679297 Free PMC article.
Virus infection, double-stranded RNA, and lipopolysaccharide each induce the expression of genes encoding IFN-alpha and -beta and chemokines, such as RANTES (regulated on activation, normal T cell expressed and secreted) and IP-10 (IFN-gamma inducible protein 10). ...
Virus infection, double-stranded RNA, and lipopolysaccharide each induce the expression of genes encoding IFN-alpha and -beta and chemokines …
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch.
Panne D, McWhirter SM, Maniatis T, Harrison SC. Panne D, et al. J Biol Chem. 2007 Aug 3;282(31):22816-22. doi: 10.1074/jbc.M703019200. Epub 2007 May 25. J Biol Chem. 2007. PMID: 17526488
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. Fitzgerald KA, et al. Nat Immunol. 2003 May;4(5):491-6. doi: 10.1038/ni921. Nat Immunol. 2003. PMID: 12692549
Single-molecule imaging of transcription factor binding to DNA in live mammalian cells.
Gebhardt JC, Suter DM, Roy R, Zhao ZW, Chapman AR, Basu S, Maniatis T, Xie XS. Gebhardt JC, et al. Nat Methods. 2013 May;10(5):421-6. doi: 10.1038/nmeth.2411. Epub 2013 Mar 24. Nat Methods. 2013. PMID: 23524394 Free PMC article.
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