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International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.
Norel X, Sugimoto Y, Ozen G, Abdelazeem H, Amgoud Y, Bouhadoun A, Bassiouni W, Goepp M, Mani S, Manikpurage HD, Senbel A, Longrois D, Heinemann A, Yao C, Clapp LH. Norel X, et al. Among authors: manikpurage hd. Pharmacol Rev. 2020 Oct;72(4):910-968. doi: 10.1124/pr.120.019331. Pharmacol Rev. 2020. PMID: 32962984 Free PMC article.
In search of pulmonary hypertension treatments: Effect of 17β-estradiol on PGI2 pathway in human pulmonary artery.
Amgoud Y, Senbel A, Bouhadoun A, Abdelazeem H, Ozen G, Savané I, Manikpurage HD, Mani S, Tran-Dinh A, Castier Y, Guyard A, Longrois D, Silverstein AM, Norel X. Amgoud Y, et al. Among authors: manikpurage hd. Prostaglandins Leukot Essent Fatty Acids. 2021 Sep;172:102321. doi: 10.1016/j.plefa.2021.102321. Epub 2021 Aug 9. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 34403986
Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses.
Guertin J, Kaiser Y, Manikpurage H, Perrot N, Bourgeois R, Couture C, Wareham NJ, Bossé Y, Pibarot P, Stroes ESG, Mathieu P, Clavel MA, Thériault S, Boekholdt SM, Arsenault BJ. Guertin J, et al. Circ Genom Precis Med. 2021 Aug;14(4):e003271. doi: 10.1161/CIRCGEN.120.003271. Epub 2021 Jul 19. Circ Genom Precis Med. 2021. PMID: 34279996
Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis.
Perrot N, Valerio V, Moschetta D, Boekholdt SM, Dina C, Chen HY, Abner E, Martinsson A, Manikpurage HD, Rigade S, Capoulade R, Mass E, Clavel MA, Le Tourneau T, Messika-Zeitoun D, Wareham NJ, Engert JC, Polvani G, Pibarot P, Esko T, Smith JG, Mathieu P, Thanassoulis G, Schott JJ, Bossé Y, Camera M, Thériault S, Poggio P, Arsenault BJ. Perrot N, et al. Among authors: manikpurage hd. JACC Basic Transl Sci. 2020 Jul 1;5(7):649-661. doi: 10.1016/j.jacbts.2020.05.004. eCollection 2020 Jul. JACC Basic Transl Sci. 2020. PMID: 32760854 Free PMC article.
Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease.
Gobeil É, Maltais-Payette I, Taba N, Brière F, Ghodsian N, Abner E, Bourgault J, Gagnon E, Manikpurage HD, Couture C, Mitchell PL, Mathieu P, Julien F, Corbeil J, Vohl MC, Thériault S, Esko T, Tchernof A, Arsenault BJ. Gobeil É, et al. Among authors: manikpurage hd. Metabolites. 2022 May 13;12(5):440. doi: 10.3390/metabo12050440. Metabolites. 2022. PMID: 35629944 Free PMC article.
Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease.
Ghodsian N, Abner E, Emdin CA, Gobeil É, Taba N, Haas ME, Perrot N, Manikpurage HD, Gagnon É, Bourgault J, St-Amand A, Couture C, Mitchell PL, Bossé Y, Mathieu P, Vohl MC, Tchernof A, Thériault S, Khera AV, Esko T, Arsenault BJ. Ghodsian N, et al. Among authors: manikpurage hd. Cell Rep Med. 2021 Nov 3;2(11):100437. doi: 10.1016/j.xcrm.2021.100437. eCollection 2021 Nov 16. Cell Rep Med. 2021. PMID: 34841290 Free PMC article.
Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases.
Gagnon E, Pelletier W, Gobeil É, Bourgault J, Manikpurage HD, Maltais-Payette I, Abner E, Taba N, Esko T, Mitchell PL, Ghodsian N, Després JP, Vohl MC, Tchernof A, Thériault S, Arsenault BJ. Gagnon E, et al. Among authors: manikpurage hd. Commun Med (Lond). 2022 Oct 13;2:130. doi: 10.1038/s43856-022-00196-3. eCollection 2022. Commun Med (Lond). 2022. PMID: 36249462 Free PMC article.
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