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Viral dependence on cellular ion channels - an emerging anti-viral target?
Hover S, Foster B, Barr JN, Mankouri J. Hover S, et al. J Gen Virol. 2017 Mar;98(3):345-351. doi: 10.1099/jgv.0.000712. Epub 2017 Apr 1. J Gen Virol. 2017. PMID: 28113044 Review.
Trafficking of ATP-sensitive potassium channels in health and disease.
Sivaprasadarao A, Taneja TK, Mankouri J, Smith AJ. Sivaprasadarao A, et al. Biochem Soc Trans. 2007 Nov;35(Pt 5):1055-9. doi: 10.1042/BST0351055. Biochem Soc Trans. 2007. PMID: 17956278 Review.
A comparative cell biological analysis reveals only limited functional homology between the NS5A proteins of hepatitis C virus and GB virus B.
Mankouri J, Milward A, Pryde KR, Warter L, Martin A, Harris M. Mankouri J, et al. J Gen Virol. 2008 Aug;89(Pt 8):1911-1920. doi: 10.1099/vir.0.2008/001131-0. J Gen Virol. 2008. PMID: 18632962
Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence.
Mankouri J, Dallas ML, Hughes ME, Griffin SD, Macdonald A, Peers C, Harris M. Mankouri J, et al. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15903-8. doi: 10.1073/pnas.0906798106. Epub 2009 Aug 26. Proc Natl Acad Sci U S A. 2009. PMID: 19717445 Free PMC article.
Expression of the NS3 protease of cytopathogenic bovine viral diarrhea virus results in the induction of apoptosis but does not block activation of the beta interferon promoter.
Gamlen T, Richards KH, Mankouri J, Hudson L, McCauley J, Harris M, Macdonald A. Gamlen T, et al. J Gen Virol. 2010 Jan;91(Pt 1):133-44. doi: 10.1099/vir.0.016170-0. Epub 2009 Sep 30. J Gen Virol. 2010. PMID: 19793904
Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection.
Mankouri J, Fragkoudis R, Richards KH, Wetherill LF, Harris M, Kohl A, Elliott RM, Macdonald A. Mankouri J, et al. PLoS Pathog. 2010 Feb 19;6(2):e1000778. doi: 10.1371/journal.ppat.1000778. PLoS Pathog. 2010. PMID: 20174559 Free PMC article.
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase.
Mankouri J, Tedbury PR, Gretton S, Hughes ME, Griffin SD, Dallas ML, Green KA, Hardie DG, Peers C, Harris M. Mankouri J, et al. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11549-54. doi: 10.1073/pnas.0912426107. Epub 2010 Jun 7. Proc Natl Acad Sci U S A. 2010. PMID: 20534540 Free PMC article.
Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.
Amako Y, Igloi Z, Mankouri J, Kazlauskas A, Saksela K, Dallas M, Peers C, Harris M. Amako Y, et al. J Biol Chem. 2013 Aug 23;288(34):24753-63. doi: 10.1074/jbc.M113.491985. Epub 2013 Jul 15. J Biol Chem. 2013. PMID: 23857585 Free PMC article.
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