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71 results
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Retinoids inhibit measles virus through a type I IFN-dependent bystander effect.
Trottier C, Colombo M, Mann KK, Miller WH Jr, Ward BJ. Trottier C, et al. Among authors: mann kk. FASEB J. 2009 Sep;23(9):3203-12. doi: 10.1096/fj.09-129288. Epub 2009 May 15. FASEB J. 2009. PMID: 19447880
A retinoid/butyric acid prodrug overcomes retinoic acid resistance in leukemias by induction of apoptosis.
Mann KK, Rephaeli A, Colosimo AL, Diaz Z, Nudelman A, Levovich I, Jing Y, Waxman S, Miller WH Jr. Mann KK, et al. Mol Cancer Res. 2003 Oct;1(12):903-12. Mol Cancer Res. 2003. PMID: 14573791
Retinoids inhibit measles virus in vitro via nuclear retinoid receptor signaling pathways.
Trottier C, Chabot S, Mann KK, Colombo M, Chatterjee A, Miller WH Jr, Ward BJ. Trottier C, et al. Among authors: mann kk. Antiviral Res. 2008 Oct;80(1):45-53. doi: 10.1016/j.antiviral.2008.04.003. Epub 2008 May 19. Antiviral Res. 2008. PMID: 18547655
Arsenic trioxide decreases AKT protein in a caspase-dependent manner.
Mann KK, Colombo M, Miller WH Jr. Mann KK, et al. Mol Cancer Ther. 2008 Jun;7(6):1680-7. doi: 10.1158/1535-7163.MCT-07-2164. Mol Cancer Ther. 2008. PMID: 18566239
Darinaparsin: a novel organic arsenical with promising anticancer activity.
Mann KK, Wallner B, Lossos IS, Miller WH Jr. Mann KK, et al. Expert Opin Investig Drugs. 2009 Nov;18(11):1727-34. doi: 10.1517/13543780903282759. Expert Opin Investig Drugs. 2009. PMID: 19780704 Review.
Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer.
Guilbert C, Annis MG, Dong Z, Siegel PM, Miller WH Jr, Mann KK. Guilbert C, et al. Among authors: mann kk. PLoS One. 2013 Dec 31;8(12):e85995. doi: 10.1371/journal.pone.0085995. eCollection 2013. PLoS One. 2013. PMID: 24392034 Free PMC article.
Arsenic trioxide: mechanisms of action.
Davison K, Mann KK, Miller WH Jr. Davison K, et al. Among authors: mann kk. Semin Hematol. 2002 Apr;39(2 Suppl 1):3-7. doi: 10.1053/shem.2002.33610. Semin Hematol. 2002. PMID: 12012315 Review.
Trolox selectively enhances arsenic-mediated oxidative stress and apoptosis in APL and other malignant cell lines.
Diaz Z, Colombo M, Mann KK, Su H, Smith KN, Bohle DS, Schipper HM, Miller WH Jr. Diaz Z, et al. Among authors: mann kk. Blood. 2005 Feb 1;105(3):1237-45. doi: 10.1182/blood-2004-05-1772. Epub 2004 Oct 5. Blood. 2005. PMID: 15466933
A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines.
Diaz Z, Mann KK, Marcoux S, Kourelis M, Colombo M, Komarnitsky PB, Miller WH Jr. Diaz Z, et al. Among authors: mann kk. Leukemia. 2008 Oct;22(10):1853-63. doi: 10.1038/leu.2008.194. Epub 2008 Jul 17. Leukemia. 2008. PMID: 18633430
Trolox enhances the anti-lymphoma effects of arsenic trioxide, while protecting against liver toxicity.
Diaz Z, Laurenzana A, Mann KK, Bismar TA, Schipper HM, Miller WH Jr. Diaz Z, et al. Among authors: mann kk. Leukemia. 2007 Oct;21(10):2117-27. doi: 10.1038/sj.leu.2404891. Epub 2007 Aug 9. Leukemia. 2007. PMID: 17690699
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